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2016, Number 3

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Med Int Mex 2016; 32 (3)

Analysis of the hemodynamic behavior during tilt test according to subtypes of disautonomic response (study REDIS-2, dysfunctional response, subanalysis of the study REDIS)

Solís-Ayala E, García-Frade RLF
Full text How to cite this article

Language: Spanish
References: 10
Page: 307-317
PDF size: 937.27 Kb.


Key words:

disautonomy, orthostatic intolerance, vasovagal syncope, postural orthostatic tachycardia syndrome, tilt test.

ABSTRACT

Background:For some time now, regarding to the disautonomic syndrome, the variety of clinical manifestations have become less mere observations, the knowledge we currently have is based on some large studies conducted in many countries including ours. This have generated that we can now diagnose the type of disautonomic response and thus, choose the appropriate treatment for our patients. The REDIS study analyzed 1,647 tilt tests in which 71.5% were women. Of the analyzed tests 43% were vasovagal reaction, 38% were orthostatic intolerance (OI), and 4% were postural orthostatic tachycardia syndrome (POTS).
Objetive: To analyze the behavior of the vital signs during tilt test according to the subtype of disautonomic response (VV, OI, POTS) in concordance to the REDIS study.
Material and Method: A retrospective, observational study done at Hospital Ángeles Pedregal, Mexico City, for which 1,660 reports of tilt test were reviewed by measuring vital signs at the beggining of the test, at 70° and then each 5 and 10 minuts during the same.
Results: The difference between vital signs in the four groups during tilt test was statistically significant (p=0.0001), and also between the symptoms and diagnosis.
Conclusion: In those patients with suggestive symptoms of disautonomy such as fatigue, dizziness, nausea, diaphoresis and cephalea we must conduct a tilt test to prove such dysfunction and establish the type of diagnosis, because there are evident hemodynamic differences among the variety of types which demands different and more specific treatments for the adequate control of the patients.


REFERENCES

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  2. Grubb B. Neurocardiogenic syncope. N Engl J Med 2005;352:1004-1010.

  3. Stewart J. Chronic orthostatic intolerance and the postural tachycardia syndrome (POTS). J Pediatr 2004;145:725-730.

  4. Weimer L, Williams O. Syncope and orthostatic intolerance. Med Clin North Am 2003;87:835-865.

  5. Weimer L, Zadeh P. Neurological aspects of syncope and orthostatic intolerance. Med Clin N Am 2009;93:427-449.

  6. García-Frade LF, Solís-Ayala E, González-Hermosillo, et al. La disautonomía en el mundo real. Med Int Mex 2013;29:469- 472.

  7. Ojha A, McNeeley K, Heller E, et al. Orthostatic syndromes differ in syncope frequency. Am J Med 2010;123:245-249.

  8. Fayyaz K, Amjad M, Ali K. Heart rate and blood pressure responses to orthostatic stress during head-up tilt test. Pak J Physiol 2012;8(2).

  9. Nilsson D, Sutton R, Tas W, et al. Orthostatic changes in hemodynamics and cardiovascular biomarkers in dysautonomic patients. PloS ONE 10(6):e0128962.

  10. Sheldon R, Grubb B, Olshansky B et al. 2015 Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Treatment of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia, and Vasovagal Syncope. Hearth Rhythm 2015;12:41-54.




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Med Int Mex. 2016;32