Genis-Mendoza A, Nicolini H, Tovilla-Zárate CA, López-Narváez ML, González-Castro TB

Language: Spanish
References: 24
Page: 329-333
PDF size: 77.82 Kb.

ABSTRACT

Introduction: The feeding behavior in humans is complex, with psychological, social, and cultural factors. This pathology consists of the desire to eat (reinforcement/reward) and the control of the act of eating (inhibitory control). It is well known that blocking post-synaptic D2 receptors in the nucleus accumbens induces a decrease of craving behavior. Due to this, to test hypothesis we measured the expression of the DRD2 gene and the expression of the type of feeding factor in a group of Mexican twins. Methods: In the study were included 18 pairs of twins (n = 36), reared together (at least up to 18 years old); native to Mexico City; to whom we applied the three factors of food instrument. Results: We observed a significant correlation between the “uncontrolled” factor and expression of the DRD2 gene (p ‹ 0.03). Conclusion: Therefore, we propose that the expression of the DRD2 gene in subjects is a linkage to the type of feeding factor.

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