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Colegio de Medicos y Cirujanos República de Costa Rica

2016, Number 619

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Rev Med Cos Cen 2016; 73 (619)

Síndrome de Sjögren primario

Pizarro MD

Language: Spanish
References: 18
Page: 395-401
PDF size: 176.66 Kb.


ABSTRACT

Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by ocular and oral dryness, signs attributed to inflammatory process in the tear and salivary glands. Near to 20- 40% of patients have severe extraglandular manifestations that threats patient’s life. The disease can present as pSS or associated with other autoimmune diseases, in what would be a secondary Sjögren’s syndrome. Glandular involvement is associated with different systemic autoimmune phenotypes, making difficult patients evaluation. This complexity has made it difficult to identify a homogeneous group of patients, with a common pathogenesis and prognosis, and ultimately, has hampered the development of criteria for classification and diagnosis of the disease. Now days, misdiagnosis is given in many cases before finding the diagnosis of SSp. Therefore, it is important to summarize in this review the main clinical manifestations, diagnosis and treatment of an entity that affects our seniors and might be going unnoticed.


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