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2016, Number 4

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Rev Ciencias Médicas 2016; 20 (4)

Tissue engineering with adult stem cells and Biograft-G in alveolar bone regeneration

Morejón ÁFC, Amado LL
Full text How to cite this article

Language: Spanish
References: 13
Page: 508-514
PDF size: 288.00 Kb.


Key words:

tissue engineering, stem cells, regenerative medicine.

ABSTRACT

Introduction: the healing of an alveolus after a tooth extraction is characterized by internal changes, leading to bone formation inside the alveolus and external changes leading to the loss of height and width of the alveolar crest. This reparative process shows two important phenomena: osteoclastic reabsorption process and the interruption of the vascularization provided to the alveoli through the periodontal ligament.
Objective: to investigate in the bone formation of alveolar cavities of the jaws from the therapeutic use of adult stem cells with Biograft-G at alveolar level.
Method: a patient requiring multiple dental extractions in the mandibular region was presented. Autotransplantation of adult stem cells with Biograft-G was placed at the level of dental alveoli, and the patient was clinically and radiographically examined at the level of the alveoli after tooth extraction, performing a prior assessment and preparation of the patient by hematology and transfunctional medicine service. The patient's clinical and radiological evolution is presented in graphics.
Results: adult stem cells going along with the osteoconductive activity of Biograft-G induce bone regeneration in the alveolar cavities of jaws, maintaining better horizontal and vertical dimensions of the alveolar crest.
Conclusions: this study confirms the use of adult stem cells with Biograft-G in the bone regeneration of alveolar cavities of the jaws; it is an effective method for alveolar preservation, opening new perspectives for the treatment of other conditions of the maxillofacial region as well.


REFERENCES

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Rev Ciencias Médicas. 2016;20