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2016, Number 1

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Rev Med MD 2016; 7.8 (1)

Adipose tissue macrophages, associated with obesity and metabolic disorders

Solís-Martínez R, Hernández-Flores G, Jiménez-Luevano MÁ, Ortiz- Lazareno PC, Cancino-Marantes M, Cruz-Gálvez CC, Bravo- Cuellar A

Language: Spanish
References: 13
Page: 11-15
PDF size: 525.85 Kb.


ABSTRACT

The prevalence of obesity has increased throughout the world in recent years. The accumulation of macrophages in adipose tissue plays a key to predispose a state of subclinical low-grade inflammation paper. The polarization of these cells into a proinflammatory phenotype, stimulates the production and secretion of cytokines and metabolic markers that cause deregulation of metabolism, promoting the emergence of metabolic diseases such as type 2 diabetes mellitus and atherosclerosis.


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