Garza MME, López E, Figueroa V, Feria G, Méndez C, Negrete O, León F

Language: Spanish
References: 8
Page: 427-430
PDF size: 54.67 Kb.

ABSTRACT

Introduction. The prostatic specific antigen (PSA) is the cornerstone in prostate cancer (PCa) detection. To increase the sensibility and specificity of this assay, the free percentage, age adjusted, PSA velocity, total density and transitional zone (TZ) density have been used. Objectives. To analize the impact of the PSA density and transitional zone density in the diagnosis of PCa. Patients and methods. We analized the prostatic volume, PSA level, PSA density and TZ density and pathology report in patients who underwent prostatic biopsy at our institution. Results. We included 98 patients in our study and found a statistical difference in the relation of PSA density-cutoff 0.15- (p ‹ 0.001, RR 1.63), TZ density -cutoff 0.30- (p = 0.001) and PCa. Conclusions. In our population, PSA density and TZ density are useful to predict the probability of PCa in patients with PSA level above 4 ng/dL.

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