medigraphic.com
SPANISH

Mediciego

ISSN 1029-3035 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2017, Number 1

<< Back Next >>

Mediciego 2017; 23 (1)

Cutaneus metastases due to a renal cell carcinoma

Rosales TP, Pila PR, Pila PR, Artola GJ, León AP
Full text How to cite this article

Language: Spanish
References: 9
Page: 30-35
PDF size: 193.91 Kb.


Key words:

renal cell carcinoma/diagnosis, neoplasm metastasis/diagnosis, skin neoplasm/secundary, case reports.

ABSTRACT

Introduction: renal adenocarcinoma (hypernephroma or Grawitz tumor) is the most frequent tumor in adults; it represents 90-95% of all kidney tumors and 2-3% of all human cancers.
Objective: to present a case of renal adenocarcinoma with initial extra-renal manifestations in the form of multiple cutaneous metastases, of interest because this is a rare form of presentation of the disease.
Case presentation: a 70 year-old patient, retired, with no personal or family history of interest; for six months he has presented lesions on the skin of the anterior wall of the trunk and fever of 38-39 °C. The physical examination revealed that the patient presented malnutrition, asthenia, anorexia, nodular and erythematous skin lesions that were discretely pediculated, pulsatile, nonpainful to pressure, well delimited and non-ulcerated. The abdominal ultrasound showed a solid mass in the upper pole of the kidney. Exeresis was performed, and the results of the immunohistochemical and anatomopathological tests showed the presence of positive vimentin and cytokeratin, as well as the histological compatibility of the lesion with metastases of renal cell carcinoma. Nephrectomy of the right kidney was performed; the anatomopathological study of the sample confirmed that it was a renal clear-cell carcinoma.
Conclusions: it should be taken into account that the appearance of cutaneous metastatic lesions as an initial presentation of renal adenocarcinoma is very rare, so the presence of these lesions should be a warning sign for specialists.


REFERENCES

  1. Anglada Curado FJ, Campos Hernández P, Prieto Castro R, Carazo Carazo JL, Regueiro López JC, Vela Jiménez F, et al. Nuevos patrones epidemiológicos y factores de riesgo en cáncer renal. Actas Urol Esp [Internet]. May 2009 [citado 3 Nov 2015];33(5):459-67. Disponible en: https://www.researchgate.net/profile/Juan_Regueiro_Lopez/publication/26720425_New_epid emiologic_patterns_and_risk_factors_in_renal_cancer/links/00b7d5274d982c5021000000.pdf

  2. García Torrelles M, Beltrán Armada JR, Verges Prosper A, Santolaya García JI, Espinosa Ruiz J, Tarín Planes M, et al. Metástasis cutánea de carcinoma de células renales. Actas Urol Esp [Internet]. May 2007 [citado 3 Nov 2015];31(5):556-8. Disponible en: http://scielo.isciii.es/pdf/aue/v31n5/v31n5a18.pdf

  3. Kouroupakis D, Patsea E, Sofras F, Apostolikas N. Renal cell carcinoma metastases to the skin: a not so rare case?. Br J Urol. May 1995;75(5):583-5.

  4. Koga S, Tsuda S, Nishikido M, Matsuya F, Saito Y, Kanetake H. Renal cell carcinoma metastatic to the skin. Anticancer Res. Jun 2000;20(3B):1939-40.

  5. Bujons A, Pascual X, Martínez R, Rodríguez O, Palou J, Villavicencio H. Cutaneous metastases in renal cell carcinoma. Urol Int. 2008;80(1):111-2.

  6. Mueller TJ, Wu H, Greenberg RE, Hudes G, Topham N, Lessin SR, Uzzo RG. Cutaneous metastases from genitourinary malignancies. Urology. Jun 2004;63(6):1021-6.

  7. Andonian S, Janetschek G, Lee BR. Laparoscopic partial nephrectomy: an update on contemporary issues. Urol Clin North Am. Ago 2008;35:385-96.

  8. López JI, Ugalde A, Zhou M. Carcinomas renales con células claras. Rev Esp Patol [Internet]. 2008 [citado 3 Nov 2015];41(3):169-82. Disponible en: https://www.researchgate.net/profile/Jose_I_Lopez/publication/257685755_Carcinomas_rena les_con_celulas_claras/links/0a85e53149d6a5d96e000000/Carcinomas-renales-con-celulasclaras. pdf

  9. Hu SC, Chen GS, Wu CS, Chai CY, Chen WT, Lan CC. Rates of cutaneus metastases from different internal malignancies: experience from a Taiwanese Medical Center. J Am Acad Dermatol [Internet]. Mar 2009 [citado 3 Nov 2015];60(3):379-87. Disponible en: https://www.clinicalkey.es/service/content/pdf/watermarked/1-s2.0- S019096220801236X.pdf?locale=es_ES




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Mediciego. 2017;23