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>Journals >Archivos en Medicina Familiar >Year 2016, Issue 3

Zúñiga RNE, Ponce RER, Jiménez GI, Acevedo GO, Vicenteño AH
Determination of Cystatin C as a Predictor of Renal Function in Patients with Type 2 Diabetes Mellitus
Arch Med Fam 2016; 18 (3)

Language: Español
References: 15
Page: 55-63
PDF: 171.56 Kb.

Full text


Objective: To determine plasma levels of cC in patients with Diabetes Mellitus. Methods: Study Design: prospective, cross-sectional, comparative and observational. Sample: nonrandom, 111 patients with type 2 diabetes, two groups: hospital and clinic, outpatient. Variables: measurement of renal function and metabolic control partners. Measurement: serum determinations of cC. Analysis: descriptive and inferential (student T test, U of Mann-Whitney). Pearson correlation. Results: There were significant differences in values for cC in patients with adequate metabolic control and in the clinic compared with hospital: Glycosylated hemoglobin (p = 0.015), total cholesterol (p = 0.030) and triglycerides (p = 0.001). Moderate inverse association between cC and creatinine clearance (Pearson correlation = - .436, p = 0.018). Conclusions: The age and metabolic control are important markers for determining initial kidney damage in asymptomatic patients. cC is a prognostic marker of early renal damage in patients with type 2 diabetes, compared with the gold standard (creatinine clearance).

Key words: Cystatin C, Type 2 Diabetes, Kidney Failure.


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>Journals >Archivos en Medicina Familiar >Year 2016, Issue 3

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