2016, Number 54
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ABSTRACTIntroduction. Most of the systemic complications during dental treatments are caused by the use of the local anesthetic, with the most frequent cardiovascular alterations. The causes of complications have been attributable to the amount of endogenous catecholamines and the vasoconstrictor included in anesthetic agents. Objective. Compare variations in vital signs and oxygen saturation capillary healthy young adult patients, after administration of mepivacaine with and without epinephrine. Methods. Randomized controlled clinical trial, in healthy young adults. Each individual is taking vital signs and oxygen saturation capillary twice; pre-anesthetic infiltration and 10 minutes later. Group 1 was employed mepivacaine with epinephrine and the mepivacaine without vasoconstrictor Group 2: Two groups were formed randomly. Results. A total of 62 subjects, 66.1 % female and 33.9 % male were included, aged 23.06 ± 2.67 years of age, two groups randomly with 31 subjects each were formed. In order to compare the values of vital signs and oxygen saturation of the capillary before and after anesthetic administration in each group, paired t-test was performed without statistically significant differences. To compare changes in vital signs and oxygen saturation of capillary in both groups, the differences of the final signal from initial was calculated; this new value is subjected to a Student t test and found statistically significant differences between the differences in capillary oxygen saturation between the two groups (0.87 ± 3.05 and -0.35 ± 1.08, t = -2.107, p = 0.039). Conclusions. The use of mepivacaine with epinephrine at the time of anesthetic blockade significantly increases the value of capillary oxygen saturation without significant changes in vital signs.
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