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Órgano Ofical de la Facultad de Estomatología de la Benemérita Universidad Autónoma de Puebla
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2016, Number 54

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Oral 2016; 17 (54)

Mepivacaine effects with and without vasoconstrictor in vital signs of young adults

Cenoz UE, Oliva OKI, Núñez MJM, Ensaldo CE, Osorno EC, Smith PFR
Full text How to cite this article

Language: Spanish
References: 14
Page: 1350-1353
PDF size: 468.97 Kb.


Key words:

dental anesthesia, mepivacaine, epinephrine, vital signs, oximetry.

ABSTRACT

Introduction. Most of the systemic complications during dental treatments are caused by the use of the local anesthetic, with the most frequent cardiovascular alterations. The causes of complications have been attributable to the amount of endogenous catecholamines and the vasoconstrictor included in anesthetic agents. Objective. Compare variations in vital signs and oxygen saturation capillary healthy young adult patients, after administration of mepivacaine with and without epinephrine. Methods. Randomized controlled clinical trial, in healthy young adults. Each individual is taking vital signs and oxygen saturation capillary twice; pre-anesthetic infiltration and 10 minutes later. Group 1 was employed mepivacaine with epinephrine and the mepivacaine without vasoconstrictor Group 2: Two groups were formed randomly. Results. A total of 62 subjects, 66.1 % female and 33.9 % male were included, aged 23.06 ± 2.67 years of age, two groups randomly with 31 subjects each were formed. In order to compare the values of vital signs and oxygen saturation of the capillary before and after anesthetic administration in each group, paired t-test was performed without statistically significant differences. To compare changes in vital signs and oxygen saturation of capillary in both groups, the differences of the final signal from initial was calculated; this new value is subjected to a Student t test and found statistically significant differences between the differences in capillary oxygen saturation between the two groups (0.87 ± 3.05 and -0.35 ± 1.08, t = -2.107, p = 0.039). Conclusions. The use of mepivacaine with epinephrine at the time of anesthetic blockade significantly increases the value of capillary oxygen saturation without significant changes in vital signs.


REFERENCES

  1. Takahashi, Y., Nakano, M., Sano, K., Kanri, T. The effects of ephinephrine in local anesthetics on plasma catecholamine and hemodynamic responses. Odontology 2005; 93:72-79

  2. Akinmoladum, V.I., Okoje, V.N., Akinosum, O.M., Adisa, A.O., Uchendu, O.C. Evaluation of the haemodynamic and Metabolic Effects of Local Anaesthetic Agent in Routine Dental Extractions. J. Maxillofac. Oral Surg. 2012.

  3. Pérusse, R., Goulet, J.P., Turcotte, J.Y. Oral Surg Oral Med Oral Pathol, 1992; 74: 679-86.

  4. Torres, L.G., Serrera, F.M., Machuca, P.G., Corcuera, F., J.R., Machuca, P. C., Castillo, O.R., Gutiérrez, P., J.L. Cardiovascular effect of dental anesthesia with articaine (40 mg with epinefrine 0,5 mg% and 40 mg with epinefrine 1mg%) versus mepivacaine (30 mg and 20 mg with epinefrine 1 mg%) in medically compromised cardiac patientes: A crossover, randomized, single blinded study. Med Oral Patol Oral Cir Bucal. 2012 Jul 1; 17(4): 655-60.

  5. Silvestre, F.J., Salvador, M.I., Bautista, D., Silvestre, R.J. Clincal study of hemodynamic changes during extraction in controlled hypertensive patients. Med Oral Patol Oral Cir Bucal 2011 May 1; 16(3): 354-58.

  6. Malamed SF. Manual de Anestesia Local. Quinta Edición 2006. Editorial Elsevier, Madrid España.

  7. Ketabi, M., Sadighi, M., Alaie, M., Sadighi, M. Influence of local anesthetics with or withouth epinephrine 1/80000 on blood pressure and heart rate: A randomized doublé-blind experimental clinical trial. Dent Res J 2012 Jul-Aug; 9(4), 437-40.

  8. Amoian, B., Rabíee, M., Aghvami, M., Milani, S. Evaluation of hemodynamic and SpO2 variability during different stages of periodontal surgery. Journal of Indian Society of Periodontology 2013, Sep-Oct; 17(5): 612-16.

  9. Brown, R.S., Rhodus, N.L. Epinephrine and local anesthesia revisited. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 100:401-8.

  10. Meechan, J.G., Cole, B., Welbury, R.R. The influence of two different dental local anesthesic solutions on the hemodynamic responses of children undergoing restorative dentistry: a randomised, single-blind, split-mouth study. Br Dent J 2001;190: 502-4.

  11. Scaparo, H.C., Maia, R.N., de Gois, S.R., Costa, F.W., Ribeiro, T.R, Soares, E.C. Effects of mepivacaine 2% with epinephrine in the cardiovascular activity of patients undergoing third molar surgery: a prospective clinical study. J Craniofac Surg, 2014 Jan; 25(1): 9-12.

  12. Núñez-Martínez, J.M., Alfaro-Moctezuma, P.E., Cenoz-Urbina, E., Osorno-Escareño, C., Méndez-Aquino, D.A. Variación de los signos vitales asociados a la administración de anestésico local con vasoconstrictor. Revista ADM Mayo- Junio 2011/ Vol LXVIII, No 3. Pp 127-31.

  13. López-M, J.F., García, V.S., García, C.B. Anestésicos Locales en Odontología: valoración mediante pulsioximetría. Acta Odontológica Venezolana 2006; 44(1).

  14. Godzieba, A., Smektata, T., Jedrzejewski, M., Tutak, K.S. Clinical assesment of the safe use local anaesthesia with vasoconstrictor agents in cardiovascular compromised patients: A systemic review. Med Sci Monit, 2014; 20: 393-98.




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Oral. 2016;17