Ginecología y Obstetricia de México

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>Journals >Ginecología y Obstetricia de México >Year 2016, Issue 10

Martínez-Robles I, González-Ortega C, Saavedra-Campos P, Chavarría-Noriega R, Pérez-Peña E, Gutiérrez-Gutiérrez AM
Use of recombinant luteinizing hormone (rLH) in controlled ovarian hyperstimulation for IVF or ICSI
Ginecol Obstet Mex 2016; 84 (10)

Language: Español
References: 35
Page: 630-638
PDF: 270.55 Kb.

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Objetive: Determine the effects of LHr in a conventional protocol with FSHr in patients ›35 years of age for IVF/ICSI.
Material and Method: Retrospective, comparative and observational study of cases and control, it was performed at Instituto Vida, Leon, Guanajuato from September 2012 to March 2014 in patients ›35 years of age. 120 patients were included in their first cycle of IVF/ICSI; 52 patients received 300 UI of FSHr / 150 UI of LHr (study group) and 68 patients received 300 UI of FSHr (control group).
Results: With similar number of mature oocytes, fertilization rate was higher (84.6%) in FSHr/LHr group compared to FSHr group (78.5%) with statistically significant differences (p‹0.01). Better pregnancy rate (53.8 vs 35.2%; p‹0.02) was also found in the study group, as well as implantation (26.5% vs 16.3%; p‹0.02) and birth rate (40.4% vs 22.1%; p‹0.03).
Conclusion: According to our results, we consider that it´s appropriate to use LHr during COH protocols with FSHr in women over 35 years old who will undergo IVF/ICSI due to the increase of pregnancy, implantation and live birth rates.

Key words: Controled ovarian stimulation, Gonadotropin, Luteinizing hormone, In vitro fertilization, Advance age.

>Journals >Ginecología y Obstetricia de México >Year 2016, Issue 10

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