Gómez-Alarcón A, González-Mirasol E, Arenas-Gómez B, López-Grande J, Gómez-García MT, González de Merlo G

Language: Spanish
References: 27
Page: 717-729
PDF size: 509.51 Kb.

ABSTRACT

Objetive: The main objective of this task consists on reviewing the existing literature in which the possible benefits of the antithrombotic therapy are studied in the prevention of complications caused by the placenta in order to acquire an acceptable clinical training and in order to suggest different areas of study related to this topic in a future.
Material and Method: In order to carry out this revision, a search of several studies published by Pubmed has been done. Clinical trials controlled in which it has been compared the possible benefit of the antithrombotic prenatal therapy opposite to the expectant conduct, in women with obstetric unfavorable precedents, with the aim to evaluate the prevention of complications caused by the placenta. In this revision, articles in which the effects of the heparin in techniques of assisted reproduction, abortions of repetition in the first trimester, antiphospholipid antibodies and thromboembolic venous diseases have not been included.
Results: After our research, 8 articles have been chosen with a total sample of 1178 women. Our revision shows a significant statistically reduction in the recurrence of hypertensive states of pregnancy (EHE), serious pre-eclampsia and minor for the gestational age (PEG) in those women who receive treatment with heparin during the pregnancy oppose to others who did not receive.
Conclusion: In spite of the fact that there seems to exist a decrease of recurrence of complications caused by the placenta such as EHE and PEG with the use of heparin, it is important to explain that in every clinical test included in our review, both the obstetric precedents, and the intervention, as well as the evaluated results are far between them for what the interpretation of the results must be done warily.

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