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2017, Number 4

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Rev Med MD 2017; 8.9 (4)

Neurocutaneous melanosis

Márquez-Palacios RE, Fajardo-Fregoso BF, Chávez-Castillo M, Gálvez-López AG, Ceja-Moreno H, Avilés-Martínez KI
Full text How to cite this article

Language: Spanish
References: 8
Page: 182-186
PDF size: 864.07 Kb.


Key words:

arachnoiditis, hydrocephalus, neurocutaneous melanosis, nevus.

ABSTRACT

Neurocutaneous melanosis is characterized by proliferation of melanocytes and melanin deposits in central nervous system associated to giant melanocytic nevus. We present the case of a 3 year old male previously healthy with the presence of cutaneous nevi in different localizations which presented with progressive headache and alteration in mental status in which infiltration of melanin to central nervous system was documented.


REFERENCES

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  2. Kadonaga J, Frieden I. Neurocutaneous melanosis: Definition and review of the literature. Journal of the American Academy of Dermatology. 1991;24(5):747- 755.

  3. Bekiesinska-Figatowska M, Szczygielski O, Boczar M. Neurocutaneous melanosis in children with giant congenital melanocytic nevi. Clinical Imaging. 2014;38(2):79-84.

  4. Acosta F, Barkovich A, Frieden I. Neurocutaneous melanosis presenting with hydrocephalus. Journal of Neurosurgery: Pediatrics. 2005;102(1):96-100.

  5. Chen Y, Woodley-Cook J, Sgro M. Sonographic and magneti cresonance imaging findingsof neurocutaneous melanosis. Radiology Case Reports. 2016;11(1):29-32.

  6. Küsters-Vandevelde H, Willemsen A, Groenen P. Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor. Acta Neuropathologica Communications. 2014;2(1).

  7. van Engen-van Grunsven A, Rabold K, Küsters- Vandevelde H. Copy number variations as potential diagnostic and prognostic markers for CNS melanocytic neoplasms in neurocutaneous melanosis. Acta Neuropathologica. 2016;133(2):333- 335.

  8. 8 . Pavlidou E, Hagel C, Papavasilliou A. Neurocutaneous Melanosis: Report of Three Cases and Up-to-date Review. Journal of Child Neurology. 2008;.(2): 256-258.




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C?MO CITAR (Vancouver)

Rev Med MD. 2017;8.9