Carrazco-Ibarra L, Terrazas-Estrada JJ, Medina-García G, Cruz-Santiago J

Language: Spanish
References: 20
Page: 53-59
PDF size: 223.36 Kb.

ABSTRACT

Background: The prevalence of chronic kidney disease is growing and the number of patients that need kidney transplant is becoming larger. People who are candidates for solid organ transplant must be screened for detection of latent tuberculosis infection with tuberculin skin test (TST). Aim of the study: 1. To determine the number of cumulative cases of latent tuberculosis in kidney transplant candidates in the last five years. 2. To define the treatment adherence percentage in kidney transplant candidates infected by latent tuberculosis in the last five years. Material and methods: We performed a retrospective cohort study searching files from renal transplant candidates. In patients with positive tuberculin skin test we ruled out the active form of tuberculosis. Patients with latent tuberculosis were given isoniazid or rifampicin during nine months and adherence was investigated. Statistical analysis: descriptive statistics. Results: The percentage of patients with latent tuberculosis infection was 30.2% (33/109). One patient with positive TST was diagnosed with active tuberculosis, Sixty percent of patients with active tuberculosis had malnutrition. The adherence to latent tuberculosis infection treatment was 93%. Four patients were found with active tuberculosis verified with microbiologic study, one with positive TST and three with negative TST. Conclusions: The prevalence of positive TST in kidney transplant candidates was inferior to the one reported in general population. More than half of the kidney transplant candidates with a positive TST were found with malnutrition. Adherence to latent tuberculosis infection treatment was higher than the one reported.

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