Peña-Pérez ML, Saucedo-Rodriguez LR, Jauregui-Franco R, Zepeda-Rea M, Aguilera-Partida J

Language: Spanish
References: 11
Page: 85-88
PDF size: 678.85 Kb.

ABSTRACT

Pemphigus is an autoimmune disease characterized by the formation of subepithelial and mucosal blisters and the deposition of immunoglobulins and complement in the basement membrane of the epidermis and mucosa. The definitive diagnosis is made by biopsy. We intend to report two cases of ocular pemphigus, its clinical manifestations, evolution, and management; emphasizing the importance of timely systemic treatment. We report two patients who presented with eye pain and visual loss. The first patient, previously under immunosuppressive treatment, presents with a corneal ulcer in their right eye; immunosuppressive therapy is maintained, and a posterior scleral patch with conjunctival flap is placed. The second patient presents with conjunctival alteration and corneal scarring, pemphigus vulgaris is diagnosed and immunosuppressive treatment is initiated. Ocular pemphigus should be considered as a possible cause of a cicatricial corneal disease, therefore performing a biopsy is recommended. Interdisciplinary and timely treatment is essential to reduce complications that endanger the function of the organ.

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