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Academia Mexicana de Neurología, A.C.

2017, Number 6

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Rev Mex Neuroci 2017; 18 (6)

Seizures neonatal: etiology, electroencephalography patterns and evolution

Aguilar-Fabré L, Rodríguez-Valdés RF, Rivera-Alés L, Galán-García L, Cárdenas GL, Aguilar-Fabré K, Hernández-Montiel HL

Language: Spanish
References: 24
Page: 41-47
PDF size: 560.78 Kb.


ABSTRACT

Introduction: Neonatal seizures (NC) constitute the clinical expression par excellence of a dysfunction in the Central Nervous System and present a high incidence.
Objective: To review etiology, electroencephalographic patterns and the evolution of neonatal seizures, as well as to seek associations between CN and other neurological risk factors.
Methods: We studied 22 patients with CN. Pre, peri and post natal antecedents were collected. Electroencephalogram (EEG) was performed, classifying the results into normal, mild, moderate and severe alterations. A general linear model was used to demonstrate possible associations between seizures and other neurological risk factors.
Results: Hypoxic-ischemic encephalopathy was the most frequent etiology, approximately 40% of the subjects showed a good outcome, and the most frequent sequel was epilepsy (40.9%). EEG was normal only in 13.63% of patients. The analysis of possible statistical associations showed statistically significant associations between the EEG outcome and the patient’s evolution (p = 0.015), between gestational age and evolution (p = 0.003) as well as between birth weight and evolution p = 0.003).
Conclusions: The prediction of morbid damage has made it necessary to search for biochemical, neurophysiological and neuroimaging indicators in order to identify early lesions that threaten the satisfactory evolution of children due to morphological and functional alterations.


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