Rodríguez GA, Gómez RHB, Fernández-Guzmáno MP

Language: Spanish
References: 12
Page: 424-428
PDF size: 190.58 Kb.

ABSTRACT

Background: Chronic kidney disease is a heterogeneous set of pathophysiological processes that are accompanied by abnormalities of the renal function and progressive deterioration of the glomerular filtration rate. The most common cause of Chronic kidney disease is diabetic nephropathy; another cause of chronic nephropathy, an obstructive process that leads to tubulointerstitial damage. Urolithiasis is a multifactorial disease in which epidemiological, racial, geographic and hereditary aspects of the populations studied have been implicated. The global prevalence ranges from 13% for men to 7% for women. Risk factors for nephrolithiasis are hypercalciuria, hyperuricosuria, urinary volume, diet and genetic factors, among others. The economic impact of the disease is considerable because of the recurrence of urinary tract infections, the need for surgical extraction or lithotripsy and, in the worst case, the progression to chronic kidney disease. Objective: To determine the prevalence of kidney damage in patients with nephrolithiasis in military personnel and their successors in the Military Regional Hospital of Specialties of Monterrey, Nuevo Leon. Material and methods: All patients who were referred for nephrolithiasis in the period from September 2015 to August 2016 were evaluated through the external nephrology clinic. The files were reviewed to note the number and type of surgical procedure to which they were submitted, in addition to their sociodemographic conditions, including the comorbidities with which they were enrolled. The data were collected in an Excel spreadsheet for their analysis, obtaining descriptive statistics and Pearson correlation measurements through the SPSS2 system; we calculated the prevalence of renal damage as well as its relation with the associated risk factors. Results: Thirty patients with nephrolithiasis were included in the study, of which eight (26.6%) had a reduction in glomerular filtration rate (‹ 60 mL/min); however, it was also evidenced that there are patients with decreased GFR between 89-60 mL/min who do not strictly meet the definition of chronic kidney disease, but this condition plus associated comorbidities and proteinuria condition deterioration of the renal function, with important clinical implications eventually.

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