2017, Number 6
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Med Int Mex 2017; 33 (6)
Cardiovascular safety of non-steroidal anti-inflammatory drugs
Rubio-Guerra AF
Language: Spanish
References: 12
Page: 809-812
PDF size: 389.04 Kb.
ABSTRACT
Non-steroidal anti-inflammatory drugs are broad use drugs in the
medical practice, their main adverse effects are gastrointestinal complications;
however, in the last 10 years their cardiovascular safety
has been questioned. The results from the
Vioxx Gastrointestinal Outcomes
Research (VIGOR) trial challenged the cardiovascular safety
of Cyclooxygenase-2 (COX 2) inhibitors. In this review, the results of
the
Prospective Randomized Evaluation of Celecoxib Integrated Safety
versus Ibuprofen or Naproxen (PRECISION) trial are analysed, as well
as their impact on the latest indications for this family of drugs.
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