2017, Number 2
Bol Clin Hosp Infant Edo Son 2017; 34 (2)
Tumor Miofibroblástico Inflamatorio (TMI) de pulmón en un niño de 10 años con hipergammaglobulinemia y plaquetosis reactiva. A propósito de un caso
Blásquez AEM, Gutiérrez VD, Rendón GH, Cruz J
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Language: Spanish
References: 14
Page: 151-158
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ABSTRACT
The inflammatory myofibroblastic tumor, formerly called by Brunn “Inflammatory Pseudotumor”, is a rare neoplasia, commonly asymptomatic and therefore difficult to diagnose, with features of intermediate malignancy described histologically as the proliferation of myofibroblasts with inflammation of plasma cells, lymphocytes and eosinophils. It is more common soft tissues and viscera of children and young adults and is one of the most frequent benign tumors in infants. In spite of being benign, it has an invasive behavior, with the possibility of metastasizing, and its recurrence is high if it is not diagnosed opportunely or completely resected. In the following paperwork is presented a clinical case of a 10-year-old male with a 6-month evolution with cough in accesses, progressive dyspnea of medium effort, hemoptysis and multiple infections of upper and lower respiratory tract, treated with several antibiotic regimens, bronchodilator and inhaled steroid without improvement. Tumor is diagnosed in the lower lobe of the left lung by Angiotomography and 2 satellite lesions are identified in the upper left lobe as well as a ganglion in the lingula completely enveloping the lower lobe artery, accompanied by paraclinics with reactive platelets and hypergammaglobulinemia. Left inferior lobectomy and biopsy of upper lobe satellite lesions were performed in a first surgical procedure, and with conventional staining and immunohistochemistry, a diagnosis of inflammatory myofibroblastic tumor was performed. A second surgical intervention is performed, where the patient dies for heart rhythm disorders such as ventricular fibrillation, which did not respond to advanced cardiopulmonary resuscitation.REFERENCES
De las Heras Carballo T, Brea-Álvarez B, Tunon-Gómez M, Moeinvaziri M , EscribanoPérez M, Rodríguez- Lizarbe I. Enfermedades inflamatorias de estirpe linfoide con afectación del sistema nervioso central. NO LINFOMAS. Presentación Electrónica Educativa. Sociedad Española de Radiología médica. 2014; 6-7.