Hernández-Huerta F, Ruiz-Bedolla E, Cruz-López A, Vilchis-Ordoñez A, Almanza Gutiérrez Z, López-Martínez B, Parra-Ortega I

Language: Spanish
References: 5
Page: 169-180
PDF size: 455.60 Kb.

ABSTRACT

In the Children’s Hospital of Mexico «Federico Gómez» (HIMFG), we look for analytical platforms to meet quality requirements, satisfying the needs of the laboratory, patients and physicians. The comparison of results between platforms allows knowing the similarity between the methodologies used in each of them. For this reason, we performed a comparison of the results of patient samples between the Architect c8000^® and Au480^® platforms and the Dimension RXL Max^® one. Material and methods: We used 60 pediatric patient samples with any visual characteristic in the serum associated with pathology, such as jaundice or hemolysis. The platforms evaluated, Architect c8000^® and Au480^®, were compared to the platform installed in the clinical chemistry laboratory of the HIMFG (Dimension RXL Max^®). Results: There was a considerable difference between the results in the direct bilirubin and ALT methodologies in the Architect c8000^® platform, while for the Au480^® platform, the difference was observed for direct bilirubin, GGT and ALP methodologies. Pearson’s correlation coefficient and slope suggest a good correlation between both platforms. The Architect c8000^® platform proved to be the fastest. The hydration time of the reactants in tablet presentation was identified as a decisive aspect for the speed of the process of the Dimension RXL Max^® platform. Conclusions: The evaluation of the platforms prior to their acquisition allows having knowledge and sustenance of the characteristics of each one of them, locating the points of improvement and the existing limitations. The processing time of a defined number of samples is decisive to know the future performance of the platforms.

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