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ISSN 0188-2198 (Print)

2018, Number 1

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Rev Mex Cardiol 2018; 29 (1)

Allergic myocardial ischemia secondary to ibuprofen, Kounis syndrome. Case report

Martínez-Torres PS, Hernández-Reyes A, Lozada-Martínez GC, García-Pérez VAY, Villavicencio-Vélez MG

Language: English
References: 11
Page: 37-40
PDF size: 318.21 Kb.


ABSTRACT

Background: Kounis syndrome was described in 1991 as the simultaneous occurrence of acute coronary events and anaphylactic allergic reactions. Reports of clinical cases and series of small cases of angina triggered by allergic reactions have been reported for many years. It encompasses concepts such as allergic angina and allergic infarction. Case report: We report a case of a 47-year-old man with a history of fixed drug eruption for 10 years. The patient attended to the hospital with a moderate-intensity chest pain, electrocardiogram was performed which was compatible with acute coronary syndrome without ST-segment elevation; it progressed favorably with treatment by protocol. The subsequent study showed hypersensitivity to non-steroidal anti-inflammatory drugs and cardiovascular tests was negative, and it was concluded as a case of allergic angina. Conclusions: Kounis syndrome is a difficult to diagnose entity that requires a high index of suspicion in the evaluation of patients with chest pain in the Emergency Department.


REFERENCES

  1. Kounis NG, Zavras GM. Histamine-induced coronary artery spasm: the concept of allergic angina. Br J Clin Pract. 1991; 45 (2): 121-128.

  2. Rico CP, Palencia HE, Rodríguez AM. Kounis syndrome. Med Intensiva. 2012; 36 (5): 358-364.

  3. Kounis NG, Soufras GD, Hahalis G. Anaphylactic Shock: Kounis hypersensitivity-associated syndrome seems to be the primary cause. N Am J Med Sci. 2013; 5 (11): 631-636.

  4. Latour-Pérez J, Cabello JB. Clinical significance of acute coronary syndrome with transient ST-segment elevation. Med Intensiva. 2011; 35 (5): 267-269.

  5. Kogias JS, Papadakis EX, Tsatiris CG, Hahalis G, Kounis GN, Mazarakis A et al. Kounis syndrome: a manifestation of drug-eluting stent thrombosis associated with allergic reaction to contrast material. Int J Cardiol. 2010; 139 (2): 206-209.

  6. Pampín HF, Jorge M, Prado R, Vázquez VR, Luis A. Acute hypersensitivity coronary syndrome: Kounis syndrome. Galicia Clin. 2014; 751: 31-32.

  7. Kounis NG. Coronary hypersensitivity disorder: the Kounis syndrome. Clin Ther. 2013; 35 (5): 563-571.

  8. Tavil Y, Turfan M, Türkoğlu S, Abaci A. Kounis syndrome secondary to amoxicillin/clavulanic acid use. Int J Cardiol. 2008; 124 (1): e4-7.

  9. Lombardi N, Pugi A, Maggini V, Lenti MC, Mugelli A, Cecchi E et al. Underdiagnosis and pharmacovigilance. The case of allergic acute coronary syndrome (Kounis syndrome). Int J Cardiol. 2013; 168 (5): 5054-5055.

  10. Cardona Dahl V; Grupo de trabajo de la Guía GALAXIA de actuación en anafilaxia. Guideline for the management of anaphylaxis. Med Clin (Barc). 2011; 136 (8): 349-355.

  11. Narváez N, Poma R, Cobos M, Salazar R, Orbe V. Case report: cardiogenic shock secondary to beta-lactam-induced kounis type I syndrome. REC-online. 2016; 2: 1-7.




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