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Federación Mexicana de Ginecología y Obstetricia, A.C.

2018, Number 03

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Ginecol Obstet Mex 2018; 86 (03)

Fetal cardiac tumors. Case series: Importance of prenatal diagnosis and perinatal impact

Juárez-García LC, Mendoza-Celaya J, Flores-Gallegos L, López-Félix J, Casillas-Barrera M, Leis-Márquez T, Erdmenger-Orellana J, García-Moreno C, Karchmer-Krivitzky S, Kably-Ambe A

Language: Spanish
References: 17
Page: 193-199
PDF size: 619.36 Kb.


ABSTRACT

Background: Fetal cardiac tumors are sporadic findings in fetal ultrasound with an incidence of 1 case per 10,000 live births. Rhabdomyomas are the most common cardiac tumors in intrauterine life (60-86%) followed by fibroids and teratomas. They almost always have spontaneous regression, can cause hemodynamic alterations and increase perinatal morbidity and mortality; in addition to its important association with the tuberous sclerosis complex, a genetic disease that presents with epilepsy and cogniti ve deficit.
Objective: To report the first Mexican series of cases of prenatal detection of rhabdomyomas.
Materials and Methods: Retrospective study consisting of the review of the records of all fetuses with prenatal diagnosis of cardiac tumors registered from January 2007 to December 2017 at the Ángeles Lomas Hospital. All patients underwent second-level ultrasound and advanced prenatal and postnatal echocardiography.
Results: Seven cases were studied, most of them with single tumors. In one case there were hemodynamic alterations during the fetal period that caused his death. In two cases, tuberous sclerosis was confirmed.
Conclusions: This is the first series of Mexican cases of fetal cardiac tumors. The findings were similar to those reported in the world literature, except that more cases of single tumors were found than multiple tumors. The size of the tumor, the number and the location can predict the perinatal prognosis and, especially, the possibility of tuberous sclerosis.


REFERENCES

  1. Gómez E. Diagnóstico prenatal de rabdomioma fetal asociado a esclerosis tuberosa. A propósito de un caso. Rev Chil Obstet Ginecol 2017: 82 (3).

  2. Galindo A , Gratacos E, Martínez JM editores. Cardiología fetal. Madrid: Marban, 2015;423-424.

  3. Jaramillo J, Cruz V. Radomioma fetal: diagnóstico prenatal y tratamiento. Rev Colomb Cardiol. 2016;23(5):454. e1-454.e5

  4. Arango C. Rabdomiomas cardiacos y esclerosis tuberosa: presentación de dos casos clínicos en recién nacido. Archivos de Medicina. 2012;12(2).

  5. DeVore G, Hakim S, Kleinman C, et al. The in utero diagnosis of an interventricular septal cardiac rhabdomyoma by means of real-time directed, M-mode echocardiography. Am J Obstet Gynecol 1982;143:967-9.

  6. Lymburner RM. Tumors of the heart: histopathological and clinical study. Can Med Ass J 1934;30:368-75.

  7. Galindo A, Gutiérrez F, Grañeras, et al. Diagnóstico prenatal de tumores cardiacos fetales: análisis retrospectivo de 18 casos. Prog Obstet Ginecol 2002;45(11):465-79.

  8. Uzun O, Wilson DG, Vujanic GM, et al. Cardiac tumours in children. Orphanet J Rare Dis 2007;2:11.

  9. Colosi E, et al. Sonographic diagnosis of fetal cardiac rhabdomyomas and cerebral tubers: a case report of prenatal Tuberous Sclerosis. J Prenat Med. (2013).

  10. Kwiatkowska J, Wałdoch A, Meyer-Szary J, Potaż P, Grzybiak M. Cardiac tumors in children: A 20-year review of clinical presentation, diagnostics and treatment. Adv Clin Exp Med. 2017 Mar-Apr;26(2):319-326.

  11. Morais MJ, Silva F, Melo M, Carriço A, Valente F. Prenatal Diagnosis of Intracardiac Tumors. Arq Bras Cardiol. 2016 Dec;107(6):605-606.

  12. Yuan SM. Fetal Primary Cardiac Tumors During Perinatal Period. Pediatr Neonatol. 2017 Jun;58(3):205-210.

  13. Yu Q , Zeng W, Zhou A, Zhu W, Liu J. Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors. Oncol Lett. 2016 Feb;11(2):1555-1559.

  14. Cotaina GL, Lázaro GE, Jiménez Ml, Savirón CR, Lerma PD. Diagnóstico de un rabdomioma intracardiaco en el primer trimestre de la gestación. Ginecol Obstet Mex. 2016 mar;84(3):180-185.

  15. Gayón VE, López CC, Carrera GJE. Rabdomioma cardiaco fetal como causa de Hydrops fetalis. Reporte de un caso. Ginecol Obstet Mex 2009;77(12):583-588.

  16. Anaya-Reyes P, Rodríguez-Rábago MJ. Diagnóstico prenatal de rabdomioma cardiaco. Reporte de un caso. Ginecol Obstet Mex 2013;81:477-481.

  17. Chao AS, Chao A, Wang TH, et al. Outcome of antenatally diagnosed cardiac rhabdomyoma: case series and a metaanalysis. Ultrasound Obstet Gynecol 2008;31:289- 295.




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