Félix-Bulman JA, Gómez-Gómez B, Ramírez-Angulo C, Toriello-Martínez S, Fragoso-González A, Díaz-Greene EJ, Rodríguez-Weber FL

Language: Spanish
References: 12
Page: 196-203
PDF size: 409.57 Kb.

ABSTRACT

Background: Nowadays, the American Diabetes Association (ADA) recognizes the use of three tests for the diagnosis of diabe tes mellitus, including the determination of glycated hemoglobin (HbA1c).
Objective: To evaluate if the established value of 6.5% of glycated hemoglobin for the diagnosis of diabetes mellitus is applicable to the Mexican population.
Material and Method: A descriptive, transversal and analytic study was done in October 2016 in persons that were subjected to a capillary test for HbA1c and serum glucose.
Results: There were included 388 subjects in whom it was determined that the age and the sex did not influence on the obtaining of a determinate level of HbA1c. Capillary HbA1c test tended to diagnose a greater number of cases of prediabetes (170 vs 63) and diabetes (27 vs 13) compared with serum glucose test, with a difference in the number of healthy persons between the two groups of 121 (191 healthy persons with HbA1C and 312 healthy persons with serum glucose); however, both variables shared a 90.2% of similarity (p ‹ 0.001). It was obtained a new threshold of HbA1C for the diagnosis of diabetes of 6.65% (with sensitivity and specificity of 76% and 97%, respectively).
Conclusion: With the new cutoff value the incidence of cases of diabetes decreased in the HbA1c group, with a reduction of 7% to 4.9% (27 to 19 cases).

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