2013, Number 2
Med Sur 2013; 20 (2)
Carrillo-Esper R, Sánchez-Zúńiga MJ
PDF size: 139.01 Kb.
ABSTRACTPreeclampsia-eclampsia remains a major cause of worldwide pregnancy related maternal mortality. Several hypothesis have been developed to explain its presentation and development, as well as various molecular basis proposed which includes alterations in the placenta implantation and imbalance in the function of certain molecules such as relaxin, matrix metalloproteinases, endothelin, nitric oxide, angiogenic factors, oxidative stress, endothelial dysfunction and genetic factors. The aim of this study was to review current concepts related to the molecular basis of preeclampsiaeclampsia