2005, Number 1
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ABSTRACTThere is a general belief that immune response decrease with aging. This knowledge has been based upon a limited number of studies involving few individuals as well as studies on cell surface markers and cytokines levels. Changes in percentage of lymphocytes subsets have been described in elderly individuals. Nonetheless, such changes have frequently been found controversial. Trying to elucidate this issue we studied lymphocyte subset in 101 clinically healthy individuals classiﬁed according to SENIEUR protocol between 0 and 102 years of age. Expression of lineage and function markers were carefully determined. Taken altogether, our results expressed and calculated by Pearson’s Coefﬁcient Correlation suggested that most immune system functions do not diminish as age progresses.
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