Agüero FA, Sancho FI, Moya SE, Brenes PF, Montero GAL, Riggioni CO

Language: Spanish
References: 8
Page: 1-5
PDF size: 447.49 Kb.

ABSTRACT

Eosinoplhilic esophagitis (EoE) is a chronic antigenmediated immune disease of the esophagus characterized by symptoms related to esophageal dysfunction, as well as significant esophageal eosinophilia.(1,2,3)It affects young men with long-standing dysphagia, recurrent food impactations and a frequent history of allergies, asthma or periphereal eosinophilia(2,3) Symptoms in EoE vary with age, as they relate to the progression of the disease from an inflammatory to a fibrostenotic phenotype over time. Prevalence reported to be similar in children and adults ~0.5-1 cases /1000 persons(1) Male sex has 3:1 preponderance, predominantly affects white men, with an onset from school age to midlife.(3) Histologically ≥15 eosinophils in at least one microscopy high-power field on esophageal biopsy specimen after a proton pump inhibitor trial is consistent with the diagnosis of EoE in the proper clinical setting.(4,6,7)We report the case of a male patient, 27 y.o., who presents multiple anaphylaxis, allergic rhinitis and conjunctivitis, seborrheic dermatitis and dysphagia; with family history of gluten allergies and multiple allergic reaction.

REFERENCES

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2. Levine M Rubesin S History and Evolution of the pharynx and Esophagus Dysphagia 2017; 32:55-72

3. Glenn T Furuta MD David A Katzka MD. Eosinophilic EsophagitisN Engl J Med. 2015; 373: 1640-1648

4. Dellon E Gonsalves N Hirano I et al. ACG Clinical Guideline: Evidenced Based Approach to the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE) Am J Gastroenterol 2013; 108: 679-692.

5. Al-Hussaini A AboZeid A Hai A How does esophagus look on barium esophagram in pediatric eosinophilic esophagitis? Abdom Radiol 2016; 41:1466-1473

6. Lucendo A Sanchez-Cazalilla M Adult versus pediatric eosinophilic esophagitis: important differences and similarities for the clinician to understand Expert Rev. Clin. Immunol. 2012; 8:733- 745

7. Philpott H Garg M Tomic D Balasubramanian S Sweis R Dysphagia: Thinking outside the box. World J Gastroenterol 2017; 23 (38): 6942-6951.

8. Matthew J Nelson MJ Miller FH et al Comparison of endoscopy and radiographic imaging for detection of esophageal inflammation and remodeling in adults with eosinophilic esophagitis Gastrointestinal Endoscopy 2017; en imprenta.