medigraphic.com
Instituto Nacional de Salud Pública

2018, Number 4

<< Back Next >>

salud publica mex 2018; 60 (4)

Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age

Gatica-Domínguez G, Rothenberg SJ, Torres-Sánchez L, Schnaas ML, Schmidt RJ, López-Carrillo L

Language: English
References: 27
Page: 388-394
PDF size: 240.41 Kb.


ABSTRACT

Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.


REFERENCES

  1. Black MM. Effects of vitamin B12 and folate deficiency on brain development in children. Food Nutr Bull. 2008;29(Suppl 2):126-31. https://doi. org/10.1177/15648265080292S117

  2. Benton D. Micronutrient status, cognition and behavioral problems in childhood. Eur J Nutr. 2008;47(3):38-50. https://doi.org/10.1007/s00394- 008-3004-9

  3. Nyaradi A, Li J, Hickling S, Foster J, Oddy WH. The role of nutrition in children’s neurocognitive development, from pregnancy through childhood. Front Hum Neurosci. 2013;7:97. https://doi.org/10.3389/ fnhum.2013.00097

  4. Dror DK, Allen LH. Effect of vitamin B12 deficiency on neurodevelopment in infants: current knowledge and possible mechanisms. Nutr Rev. 2008;66(5):250-5. https://doi.org/10.1111/j.1753-4887.2008.00031.x

  5. Strand TA, Taneja S, Ueland PM, Refsum H, Bahl R, Schneede J, et al. Cobalamin and folate status predicts mental development scores in North Indian children 12–18 mo of age. Am J Clin Nutr. 2013;97(2):310-7. https://doi.org/10.3945/ajcn.111.032268

  6. Louwman MW, van Dusseldorp M, van de Vijver FJ, Thomas CM, Schneede J, Ueland PM, et al. Signs of impaired cognitive function in adolescents with marginal cobalamin status. Am J Clin Nutr. 2000;72(3):762-9.

  7. Kvestad I, Taneja S, Kumar T, Hysing M, Refsum H, Yajnik CS, et al. Vitamin B12 and folic acid improve gross motor and problem-solving skills in young North Indian children: a randomized placebo-controlled trial. PloS One. 2015;10(6):e0129915. https://doi.org/10.1371/journal.pone.0129915

  8. Torres-Sánchez L, Rothenberg SJ, Schnaas L, Cebrián ME, Osorio E, Hernández MC, et al. In utero p, p’-DDE exposure and infant neurodevelopment: a perinatal cohort in Mexico. Environ Health Perspect. 2007;115(3):435. https://doi.org/10.1289/ehp.9566

  9. Torres-Sánchez L, Schnaas L, Cebrián ME, Hernández MC, Valencia EO, García Hernández RM, et al. Prenatal dichlorodiphenyldichloroethylene (DDE) exposure and neurodevelopment: a follow-up from 12 to 30 months of age. Neurotoxicology. 2009;30(6):1162-5. https://doi. org/10.1016/j.neuro.2009.08.010

  10. Galván-Portillo M, Torres-Sánchez L, Hernández-Ramírez RU, Anaya-Loyola MA. Cuestionario de frecuencia de consumo de alimentos para estimación de ingestión de folato en México. Salud Publica Mex. 2011;53(3):237-46. https://doi.org/10.1590/S0036-36342011000300008

  11. US Department of Agriculture. Agricultural Research Service. USDA National Nutrient Database for Standard Reference, Release 20. Nutrient Data Laboratory Home Page. 2007 [cited february, 2017]. Available from: http://www.ars.usda.gov/ba/bhnrc/ndl

  12. Bayley N. Bayley scales of infant development. San Antonio Tex, USA: Psychological Corporation, 1993.

  13. Wechsler D. WAIS-R manual: Wechsler adult intelligence scale-revised. San Antonio Tex, USA: Psychological Corporation, 1981.

  14. Totsika V, Sylva K. The home observation for measurement of the environment revisited. Child Adolesc Ment Health. 2004;9(1):25-35. https:// doi.org/10.1046/j.1475-357X.2003.00073.x

  15. Institute of Medicine. Dietary Reference Intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin and choline. Washington, DC: The National Academy Press, 1998.

  16. Willett W, Howe GR, Kushi LH. Adjustment for total energy intake in epidemiologic studies. Am J Clin Nutr. 1997;65(4):1220S-8S. https://doi. org/10.1093/ajcn/65.4.1220S

  17. Willett W, Lenart E. Reproducibility and validity of food-frequency questionnaires. 3rd ed. New York: Oxford University Press, 2013.

  18. Ramírez-Silva I, Jiménez-Aguilar A, Valenzuela-Bravo D, Martínez-Tapia B, Rodríguez-Ramírez S, Gaona-Pineda EB, et al. Methodology for estimating dietary data from the semi-quantitative food frequency questionnaire of the Mexican National Health and Nutrition Survey 2012. Salud Publica Mex. 2016;58(6):629-38. https://doi.org/10.21149/spm.v58i6.7974

  19. Del Río-García C, Torres-Sánchez L, Chen J, Schnaas L, Hernández C, Osorio E, et al. Maternal MTHFR 677C>T genotype and dietary intake of folate and vitamin B 12: their impact on child neurodevelopment. Nutr Neurosci. 2009;12(1):13-20. https://doi.org/10.1179/147683009X388913

  20. Guéant JL, Namour F, Guéant-Rodriguez RM, Daval JL. Folate and fetal programming: a play in epigenomics? Trends Endocrinol Metab. 2013;24(6):279-89. https://doi.org/10.1016/j.tem.2013.01.010

  21. Berrocal-Zaragoza MI, Sequeira JM, Murphy MM, Fernandez-Ballart JD, Abdel Baki SG, Bergold PJ, et al. Folate deficiency in rat pups during weaning causes learning and memory deficits. Br J Nutr. 2014;112(08):1323-32. https://doi.org/10.1017/S0007114514002116

  22. Iskandar BJ, Rizk E, Meier B, Hariharan N, Bottiglieri T, Finnell RH, et al. Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest. 2010;120(5):1603. https:// doi.org/10.1172/JCI40000

  23. Fenech M. Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity. Mutat Res. 2012;733(1):21-33. https://doi.org/10.1016/j.mrfmmm.2011.11.003

  24. Stabler SP. Vitamin B12 deficiency. N Engl J Med. 2013;368(2):149-60. https://doi.org/10.1056/NEJMcp1113996

  25. Mundo-Rosas V, Rodríguez-Ramírez S, Shamah-Levy T. Energy and nutrient intake in Mexican children 1 to 4 years old: results from the Mexican National Health and Nutrition Survey 2006. Salud Publica Mex. 2009;51:S530-S9. https://doi.org/10.1590/s0036-36342009001000008

  26. Institute of Medicine. Dietary Reference Intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. Washigton, DC: The National Academies Press, 2005.

  27. Villalpando S, de la Cruz V, Shamah-Levy T, Rebollar R, Contreras-Manzano A. Nutritional status of iron, vitamin B12, folate, retinol and anemia in children 1 to 11 years old: Results of the Ensanut 2012. Salud Publica Mex. 2015;57(5):372-84. https://doi.org/10.21149/spm.v57i5.7616




2020     |     www.medigraphic.com