2018, Number 4
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Rev Clin Esc Med 2018; 8 (4)
Osteosarcoma: Etiología, diagnóstico y tratamiento
de Armas L, Delgado D, Alvarado K, Cordero C
Language: Spanish
References: 18
Page: 1-5
PDF size: 293.11 Kb.
ABSTRACT
Osteosarcoma is the most common primary bone
tumor (16), a spindle cell neoplasm that produces
osteoid matrix, ie non-mineralized bone (12). they
are aggressive tumors locally and tend to produce
metastases early; the most common histological type is
the conventional one presented in 75% of cases (4, 11).
there are two major peaks of incidence, the first one
affects children and adolescents in the second decade
of life, these are mostly sporadic And occur in the
metaphysis of long bones; the second peak occurs in
the fifth or sixth decade and tends to be secondary to
radiation or to the transformation of preexisting benign
processes as in bone Paget disease, having a preference
for axial locations. Survival of patients has improved
drastically with the correct use of chemotherapy, since
at the time of diagnosis subclinical metastases are very
likely.
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