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Federación Mexicana de Ginecología y Obstetricia, A.C.

2018, Number 10

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Ginecol Obstet Mex 2018; 86 (10)

Levels of 25-hydroxyvitamin D in pregnant womens with and without gestational diabetes mellitus

Camarena-Pulido EE, Corona-Gutiérrez AA, Avilés-Almanza C, González-Moreno J, Fajardo-Dueñas S, López-Aceves LJ

Language: Spanish
References: 17
Page: 658-664
PDF size: 401.12 Kb.


ABSTRACT

Objective: To compare the levels of vitamin (25[OH]D) between patients with or without gestational diabetes.
Materiales and Methods: Analytical cross-sectional study that consisted in taking blood samples to determine and compare the concentrations of (25[OH]D) vitamin D. The sample size was previously determined considering a prevalence of 35% for vitamin D deficiency, an alpha error of 0.05 and a beta error of 0.80 for which 784 pregnant women were recruited, 394 patients with gestational diabetes and 390 without gestational diabetes.
Results: In the group of patients without gestational diabetes, 51% (n = 199) had sufficient levels, 33% (n = 129) insufficient levels and 16% (n = 62) deficient levels. In the group of patients with gestational diabetes, 12% (n = 47) had sufficient levels, 67% (n = 264) insufficient levels and 21% (n = 83) deficient levels. The results obtained show that 88.9% (n = 350) of women with gestational diabetes present with levels lower than 30 ng/mL vs 48.5% (n = 189) of the group without gestational diabetes [p ‹0.00001 OR 7.69 (IC95%: 5.3 - 11)].
Conclusions: Levels below 30 ng/mL of total vitamin D are more frequent in patients with gestational diabetes.


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