2018, Number 6
<< Back Next >>
Rev Mex Pediatr 2018; 85 (6)
Stevens-Johnson syndrome in pediatrics, a case report for the use of antiepileptic drugs
Bonilla-Rojas J, Hernández-Cabezza A, Villasís-Keever MÁ, Serret-Montoya J, Cárdenas-Navarrete R
Language: Spanish
References: 9
Page: 226-229
PDF size: 285.75 Kb.
ABSTRACT
Introduction: Most cases of toxic epidermal necrolysis and Stevens-Johnson syndrome have presentations with mucosal and skin involvement, derived from the reaction to certain drugs, which clinically constitute the same disease spectrum, although with a different degree of epidermolysis.
Case presentation: Male patient of 11 years of age, admitted to the adolescent medicine service, who developed a severe presentation with cutaneous lesions, conjunctivitis and oral lesions after the ingestion of lamotrigine; treatment was conservative, although slow, the patient progressed satisfactorily.
Conclusion: In the present case, isolation, minimal invasion and early initiation of enteral nutrition were appropriate to achieve recovery.
REFERENCES
Barbosa-Moreno L, Salas-Alanís J, Ocampo-Garza J, Ocampo-Candiani Jorge. Urgencias dermatológicas. Dermatol Rev Mex. 2015; 59: 26-38.
Smyth RM, Gargon E, Kirkham J, Cresswell L, Golder S, Smyth R et al. Adverse drug reactions in children--a systematic review. PLoS One. 2012; 7(3): e24061.
Sato S, Kanbe T, Tamaki Z, Furuichi M, Uejima Y, Suganuma E, et al. Clinical features of Stevens-Johnson syndrome and toxic epidermal necrolysis. Pediatr Int. 2018; 60(8): 697-702.
López-Mata A, Muñon-Guerrero F, Rodríguez-Rodríguez I. Evaluación y manejo inicial del niño “gran quemado”. México: Secretaría de Salud; 2010.
De la Teja-Ángeles E, Ceballos-Hernández H, Durán-Gutiérrez A, Posadas-Rojas G. Tratamiento estomatológico de los trastornos vesiculoampollosos. Síndrome de Lyell. Informe de un caso. Acta Pediatr Mex. 2005; 26(4): 184-189.
Castillo-Muñoz FI, Céspedes-Guirao FJ, Novo-Torres A, Lorda-Barraguer E. Análisis retrospectivo de 23 años de necrólisis epidérmica tóxica en la Unidad de Quemados de Alicante, España. Cir Plást Iberolatinoam. 2014; 40(3): 279-294.
Lerch M, Mainetti C, Terziroli Beretta-Piccoli B, Harr T. Current Perspectives on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. Clin Rev Allergy Immunol. 2018; 54(1): 147-176.
Tak HJ, Ahn JH, Kim KW, Kim Y, Choi SW, Lee KY et al. Rash in psychiatric and nonpsychiatric adolescent patients receiving lamotrigine in Korea: a retrospective cohort study. Psychiatry Investig. 2012; 9(2): 174-179.
Mockenhaupt M. Stevens-Johnson syndrome and toxic epidermal necrolysis: clinical patterns, diagnostic considerations, etiology, and therapeutic management. Semin Cutan Med Surg. 2014; 33(1): 10-6.
Full text