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2018, Number 1

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Enf Infec Microbiol 2018; 38 (1)

Clinical efficacy of cefditoren for skin and soft tissue infection treatment

Ventura HTR, Guevara SMI, Ranero JGA, Martínez GD, Mondragón P, Flores TLY, Galicia TJ

Language: Spanish
References: 15
Page: 12-16
PDF size: 262.91 Kb.


ABSTRACT

Cefditoren is a third-generation cephalosporin that has been prescribed for skin and soft tissue infections treatment (Staphylococcus aureus and Streptococcus pyogenes), acute pharyngitis (S. pyogenes), acute sinusitis (Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis), acute exacerbation of chronic bronchitis (S. pneumoniae, H. influenzae and M. catarrhalis), mild to moderate community acquired pneumonia (S. pneumoniae, H. influenzae, S. aureus). Experience with cefditoren treatment in mild to moderate skin and soft tissue infections is presented.
Material and Methods. Observational, longitudinal, prospective study of incident cases from August 2016 to March 2017, patients with angiological problems who also had mild to moderate skin and soft tissue infections were collected. Patients were selected by four angiologists from Mexico City in their private practice. All patients received ambulatory management, receiving cefditoren at 200 mg or 400 mg every 12 hours for 7, 14 or more days according to evolution and severity. They were evaluated weekly until their cure.
Results. Data were collected from 126 patients. Patients had a mean age of 65 years (range 40 to 90 years), 70% of the female sex, 30% of the male sex. The improvement of pain, inflammation and hyperthermia was evident in the infected areas and a clinical resolution of the infectious process was obtained in 97%, because 3% of the patients left the treatment. Four percent of the patients had minor adverse events.
Conclusions. Cefditoren was effective in the treatment of mild to moderate skin and soft tissue infections.


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