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ISSN 1684-1824 (Electronic)

2019, Number 1

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Rev Méd Electrón 2019; 41 (1)

Behavior of brain metastases in lung cancer in Matanzas

Camacho SK, García HM, Martí MAE, Herrera SA, Martí CMC

Language: Spanish
References: 23
Page:
PDF size: 143.60 Kb.


ABSTRACT

Introduction: in the last three decades, cardiovascular diseases and malignant neoplasms have become the main health problem in Cuba as a consequence of the steady improvement of the health levels, the prevention of the communicable diseases, and the increase of the life expectancy at birth; among them lung cancer stands out as the primary tumor that more frequently causes metastatic brain compromise.
Objective: to analyze the behavior of brain metastases in patients with lung cancer.
Materials and methods: a retrospective and descriptive study was carried out in 96 patients with cyto-histological diagnosis of lung cancer and brain metastases, who attended the external consultation of the Provincial Oncologic Center of Matanzas, from January 2013 to December 2016. Clinicdemographic data were obtained from the patients´ individual clinical reports and the Cancer Report document.
Results: the highest incidence of lung cancer corresponds to people aged 45-64 years; it behaves very similar both in male and in female genders, thought the first one shows more quantity of cases; white color skin predominated in both sexes. As for the brain metastases, they are more common from the fifth to the seventh decade of life.
Conclusions: brain metastasis appears from early ages and up to the elder age; the highest percent was diagnosed at the beginning of the disease, being this an important risk factor.


REFERENCES

  1. Ministerio de Salud Pública. Anuario Estadístico de Salud Cuba 2016. La Habana: Dirección Nacional de Registros Médicos y Estadísticas de Salud; 2015. [ Links ]

  2. Benavides M, Arraez MA, Herruzo I, et al. Enfoque multidisciplinar neurooncológico. España: Editorial Nova Sidonia; 2012. [ Links ]

  3. Caballero García J, Cruz García C, Morales Pérez I, et al. Tratamiento multimodal e individualizado a pacientes con metástasis encefálica. Rev Chilena de neuro-psiquiatría [Internet]. 2014 [citado 22/10/2017];52(4). Disponible en: Disponible en: https://scielo.conicyt.cl/pdf/rchnp/v52n4/art03.pdf [ Links ]

  4. Colectivo de autores cubanos. Guía cubana de cáncer de pulmón, acciones para su control. La Habana: MINSAP; 2016. [ Links ]

  5. Dawood S, Lei X, Litton JK, et al. Incidence of brain metastases as a first site of recurrence among women with triple receptor-negative breast cancer. Cancer [Internet]. 2012 [citado 22/10/2017];118(19). Disponible en: Disponible en: http://ascopubs.org/doi/abs/10.1200/jco.2011.29.15_suppl.1039 [ Links ]

  6. Castillo A, Arias DF, Leyva AA, et al. Neoplasia del pulmón. Comportamiento epidemiológico. Rev Cubana Oncol [Internet]. 2001 [citado16/04/2016];17(2). Disponible en: Disponible en: http://www.bvs.sld.cu/revistas/onc/vol17_2_01/Oncolog%EDa%202%202001.pdf #page=29 [ Links ]

  7. Lovelle I, Cordero N, Álvarez A, et al. Comportamiento de la mortalidad por tumores malignos. MediCentro [Internet]. 2007 [citado 16/04/2016];11(2). Disponible en: Disponible en: http://www.vcl.sld.cu/sitios/medicentro/pdf/Sumario/Ano%202007/v11n2a07%20 /comportamiento.pdf [ Links ]

  8. Caballero García J, de Mendoza Amat J, Cruz García O, et al. Características de la metástasis intracraneal en 14 321 autopsias realizadas en el Hospital “Dr. Luis Díaz Soto” La Habana (1962-2011). Rev Cubana de Neurología y Neurocirugía [Internet]. 2013 [citado 16/04/2018];3(2). Disponible en: Disponible en: http://www.revneuro.sld.cu/index.php/neu/article/view/157 [ Links ]

  9. García Rodríguez ME, Armas Pérez B, Armas Moredo K, et al. Oligometástasis y oligorrecurrencia en el cáncer del pulmón: ¿estados cercanos a la muerte? Rev Cubana de Cirugía [Internet]. 2014 [citado 22/01/2018];53(2). Disponible en: Disponible en: http://scielo.sld.cu/pdf/cir/v53n2/cir12214.pdf [ Links ]

  10. Caballero García J, Cruz García O, Morales Pérez I, et al. Caracterización clínico patológica e imagenológica de la metástasis encefálica. Rev Cubana de Neurología y Neurocirugía [Internet]. 2014 [citado 22/02/2018];5(1). Disponible en: Disponible en: http://www.medigraphic.com/pdfs/revcubneuro/cnn-2015/cnn151b.pdf [ Links ]

  11. Lacerda Gallardo ÁJ, Estenoz Esquivel JC, Borroto Pacheco R. Metástasis cerebral: Estudio clínico quirúrgico y anatomopatológico. Rev Cubana de Cirugía [Internet]. 2000 [citado 12/01/2018];39(2). Disponible en: Disponible en: http://scielo.sld.cu/pdf/cir/v39n2/cir03200.pdf [ Links ]

  12. Caffo O, Veccia A, Fellin G, et al. Frequency of brain metastases from prostate cancer: an 18-year single-institution experience. J Neuro-oncology [Internet]. 2013 [citado 17/8/2017];111(2). Disponible en: Disponible en: https://link.springer.com/article/10.1007/s11060-012-0994-1 [ Links ]

  13. World Health Organization. WHO Global Report on Mortality Attributable to Tobacco PAHO Cancer Country Profiles 2013 [Internet]. USA: World Health Organization; 2012 [citado 17/8/2017]. Disponible en: Disponible en: https://www.who.int/tobacco/publications/surveillance/rep_mortality_attributable/ en/ [ Links ]

  14. Comisión clínica de cáncer de pulmón. Protocolo cáncer de pulmón. Diagnóstico, tratamiento y seguimiento [Internet]. Córdoba: Comisión clínica de cáncer de pulmón; 2015 [citado 16/03/2018]. Disponible en: Disponible en: www.juntadeandalucia.es/servicioandaluzdesalud/..tumores/cancer_pulmon.pdf [ L inks ]

  15. American Cancer Society. Cáncer de pulmón no microcítico [Internet]. USA: American Cancer Society; 2016 [citado16/03/2018]. Disponible en: Disponible en: https://www.cancer.org/es/cancer/cancer-de-pulmon-no-microcitico.html [ Links ]

  16. Chi Ramírez D, Forteza Sáez M, Galán Álvarez Y, et al. Mortalidad por metástasis encefálica (La Habana, 2006-2008). Revista Cubana de Neurología y Neurocirugía [Internet]. 2014 [citado 22/03/2018];4(2). Disponible en: Disponible en: http://www.medigraphic.com/pdfs/revcubneuro/cnn-2014/cnn142d.pdf [ Links ]

  17. Hengel K, Sidhu G, Choi J. Attributes of brain metastases from breast and lung cancer. Intern J Clinical Oncol [Internet]. 2013 [citado 12/07/2017];18(3). Disponible en: Disponible en: https://link.springer.com/article/10.1007/s10147-012-0392- x [ Links ]

  18. Travis WD, Brambilla E, Nicholson AG, et al. The 2015 World Health Organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification. J Thorac Oncol. 2015;10(9). Citado en PubMed; PMID: 26291008 [ Links ]

  19. Kaal EC, Taphoorn MJ, Vecht CJ. Symptomatic management and imaging of brain metastases. J Neuro-Oncology. 2005;75(1). Citado en PubMed; PMID:16215812. [ Links ]

  20. Fink KR, Fink JR. Imaging of brain metastases. Surg Neurol Int. 2013;4(Suppl 4). Citado en PubMed; PMID: PMC3656556. [ Links ]

  21. Rangachari D, Yamaguchi N, VanderLaan PA, et al. Brain metastases in patients with EGFR-mutated or ALK-rearranged non-small-cell lung cancers. Lung cancer. 2015;88(1). Citado en PubMed; PMID: 25682925. [ Links ]

  22. Stewart JG, Sawrie SM, Bag A, et al. Management of brain metastases. Current treatment options in Neurology [Internet]. 2010 [citado 17/02/2018];12(4). Disponible en: Disponible en: https://link.springer.com/article/10.1007/s11940-010-0074- 9 [ Links ]

  23. Eastman P. New Dartmouth Atlas Report on Medicare Patients with Advanced Cancer: More Use of Hospice, but Aggressive Therapy at End of Life Continues. Oncology Times [Internet]. 2013 [citado 16/05/2016];35(19). Disponible en: Disponible en: https://journals.lww.com/oncologyimes/ Fulltext/2013/10100/New_Dartmouth_Atlas_Report_on_Medicare_Patients.9.asp x [ Links ]




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