Chao PC, Ortega CH, Gutiérrez RÁR, Casas ME

Language: Spanish
References: 9
Page: 25-33
PDF size: 413.46 Kb.

ABSTRACT

Introduction: Chronic heart failure is one of the leading causes of cardiovascular death worldwide. A paradoxical effect of the corporal weight in the mortality of these patients is considered.
Objective: To evaluate the body mass index (BMI) as a prognostic factor in the mortality of patients with chronic heart failure and the relationship with the blood concentration of interleukin 6.
Methods: A prospective cohort analytical study was conducted in patients with chronic heart failure, from January 2016 to December 2016, and they were followed up for one year. 109 patients formed the sample. Cox regression model was used for statistical analysis and statistical significance was calculated as applicable.
Results: The low weight category showed higher influence on the risk of death, OR 2,943 (CI: 1,378-6,285). The overweight-obesity variable presented OR below 1, as the body mass index increased, the IL6 concentration decreased.
Conclusions: The body mass index allows us to offer prognostic information. The lower blood concentration of interleukin 6 in obese patients with respect to normal weight may be an explanation for the higher survival of these patients.

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