Ajiz PVA, Orellana AÁR, Pulido DN, Quintal RMJ

Language: Spanish
References: 10
Page: 128-130
PDF size: 149.19 Kb.

ABSTRACT

Pemphigoid Brunsting-Perry variety is considered a localized subtype of cicatricial pemphigoid. It is characterized by the appearance of subepidermal blisters that appear predominantly in the skin of the head and neck, rarely affecting mucous. These blisters usually leave areas of atrophic scar when they heal. It is a rare pathology and the clinical manifestations are usually nonspecific, which conditions a low suspicion of this entity and propitiates the presentation of sequels such as cicatricial alopecia in those patients who show scalp involvement. Histopathology shows a subepidermal blister with mixed inflammatory infiltrate. This requires complementation with immunofluorescence in which the presence of linear deposits of IgG and C3 along the basement membrane is described, more frequently. Recently, in these lesions, it has been reported the identification of autoantigens directed not only towards elements of the lamina lucida, but also to the sublamina densa linking it as a variant of other subepidermal bullous dermatoses.

REFERENCES

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