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Revista Latinoamericana de Infectología Pediátrica

ISSN 2683-1678 (Print)
Órgano Oficial de la Sociedad
Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología
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2019, Number 2

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Rev Latin Infect Pediatr 2019; 32 (2)

Oseltamivir for the treatment of flu in children and adolescents

Tagarro A, Cruz-Cañete M, Otheo E, Launes C, Couceiro JA, Pérez C, Alfayate S
Full text How to cite this article

Language: Spanish
References: 25
Page: 48-52
PDF size: 176.58 Kb.


Key words:

Influenza, antivirals, oseltamivir, zanamivir.

ABSTRACT

The flu is usually a benign disease, but it can have serious complications. There is controversy about the benefits of antiviral treatment in children. In this work a review of the available literature has been carried out and recommendations have been elaborated using GRADE methodology on oseltamivir treatment in paediatric patients with influenza. Oseltamivir is not recommended in healthy outpatients or asthmatics with influenza or inpatients with influenza. Oseltamivir is recommended for patients with influenza and pneumonia, severe and critical underlying disease. Influenza vaccination remains the main tool in influenza prevention


REFERENCES

  1. Committee on Infectious Diseases. Recommendations for prevention and control of influenza in children, 2017-2018. Pediatrics. 2017; 140: e20172550, http://dx.doi.org/10.1542/peds.2017-2550.

  2. European Centre for Disease Prevention and Control. Expert opinion on neuraminidase inhibitors for the prevention and treatment of influenza- review of recent systematic reviews and meta-analyses. Stockholm: ECDC; 2017. Available in: http://dx.doi.org/10.2900/01723.

  3. Centers for Disease Control and Prevention. Influenza antiviral medications: summary for clinicians. [Consulted 20 October 2017]. Available in: https://www.cdc.gov/flu/professionals/antivirals/summary-clinicians.htm.

  4. Schünemann HJ, Oxman AD, Brozek J, Glasziou P, Jaeschke R, Vist GE et al., GRADE Working Group. Grading quality of evidence and strength of recommendations for diagnostic tests and strategies. BMJ. 2008; 336: 1106-1110. Available in: http://dx.doi.org/10.1136/bmj.a139.

  5. Guyatt GH, Oxman AD, Schünemann HJ, Tugwell P, Knottnerus A. GRADE guidelines: a new series of articles in the journal of clinical epidemiology. J Clin Epidemiol. 2011; 64: 380-382. Available in: http://dx.doi.org/10.1016/j.jclinepi.2010.09.011.

  6. Casalegno JS, Eibach D, Valette M, Enouf V, Daviaud I, Behillil S et al. Performance of influenza case definitions for influenza community surveillance: based on the French influenza surveillance network GROG, 2009-2014. Euro Surveill. 2017; 22 (14): 30504. Available in: http://dx.doi.org/10.2807/1560-7917.ES.2017.22.14.30504.

  7. Fitzner J, Qasmieh S, Mounts AW, Alexander B, Besselaar T, Briand S et al. Revision of clinical case definitions: Influenza-like illness and severe acute respiratory infection. Bull World Health Organ. 2018; 96: 122-128. Available in: http://dx.doi.org/10.2471/BLT.17.194514.

  8. Cohen R, Thollot F, Lécuyer A, Koskas M, Touitou R, Boucherat M et al. Impact of the rapid diagnosis downtown in the assumption of responsibility of the children in period of influenza. Arch Pediatr. 2007; 14: 926-931. Available in: http://dx.doi.org/10.1016/j.arcped.2007.02.087.

  9. De la Rocque F, Lécuyer A, Wollner C, d’Athis P, Pecking M, Thollot F et al. Impact of influenza rapid diagnostic tests (IRDT) on the diagnosis of influenza and on the management of influenza in children in ambulatory pediatric setting. Arch Pediatr. 2009; 16: 288-293. http://dx.doi.org/10.1016/j.arcped.2008.12.007.

  10. Doan Q, Enarson P, Kissoon N, Klassen TP, Johnson DW. Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department. Cochrane Database Syst Rev. 2014. Available in: http://dx.doi.org/10.1002/14651858.CD006452.pub4. CD006452.

  11. Pierron S, Haas H, Berlioz M, Ollier L, Albertini M. Impact of rapid influenza test during influenza epidemic in all febrile children less than 6 years old in a pediatric emergency department. Arch Pediatr. 2008; 15: 1283-1288. Available in: http://dx.doi.org/10.1016/j.arcped.2008.04.035.

  12. Avril E, Lacroix S, Vrignaud B, Moreau-Klein A, Coste-Burel M, Launay E et al. Variability in the diagnostic performance of a bedside rapid diagnostic influenza test over four epidemic seasons in a pediatric emergency department. Diagn Microbiol Infect Dis. 2016; 85: 334-337. Available in: http://dx.doi.org/10.1016/j.diagmicrobio.2016.03.015.

  13. Pollara CP, Piccinelli G, Rossi G, Cattaneo C, Perandin F, Corbellini S et al. Nosocomial outbreak of the pandemic Influenza A (H1N1) 2009 in critical hematologic patients during seasonal influenza 2010-2011: detection of oseltamivir resistant variant viruses. BMC Infect Dis. 2013; 13: 127. Available in. http://dx.doi.org/10.1186/1471-2334-13-127.

  14. Merckx J, Wali R, Schiller I, Caya C, Gore GC, Chartrand C et al. Diagnostic accuracy of novel and traditional rapid tests for influenza infection compared with reverse transcriptase polymerase chain reaction: a systematic review and metaanalysis. Ann Intern Med. 2017; 167: 394. Available in: http://dx.doi.org/10.7326/M17-0848.

  15. Robinson JL, Lee BE, Kothapalli S, Craig WR, Fox JD. Use of throat swab or saliva specimens for detection of respiratory viruses in children. Clin Infect Dis. 2008; 46: e61-64. Available in: http://dx.doi.org/10.1086/529386.

  16. Frazee BW, Rodríguez-Hoces de la Guardia A, Alter H, Chen CG, Fuentes EL, Holzer AK et al. Accuracy and discomfort of different types of intranasal specimen collection methods for molecular influenza testing in emergency department patients. Ann Emerg Med. 2018; 71: 509-170. Available in: http://dx.doi.org/10.1016/j.annemergmed.2017.09.010.

  17. Heinonen S, Silvennoinen H, Lehtinen P, Vainionpää R, Vahlberg T, Ziegler T et al. Early oseltamivir treatment of influenza in children 1-3 years of age: A randomized controlled trial. Clin Infect Dis. 2010; 51 :887-894. Available in: http://dx.doi.org/10.1086/656408.

  18. Jefferson T, Jones MA, Doshi P, del Mar CB, Hama R, Thompson MJ et al. Neuraminidase inhibitors for preventing and treating influenza in adults and children. Cochrane Acute Respiratory Infections Group, ed. Cochrane Database Syst Rev. 2014; Available in: http://dx.doi.org/10.1002/14651858.CD008965.pub4.

  19. Muthuri SG, Venkatesan S, Myles PR, Leonardi-Bee J, al Khuwaitir TS, al Mamun A et al. Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data. Lancet Respir Med. 2014; 2: 395-404. Available in: http://dx.doi.org/10.1016/S2213-2600(14)70041-4.

  20. Louie JK, Yang S, Samuel MC, Uyeki TM, Schechter R. Neuraminidase inhibitors for critically ill children with influenza. Pediatrics. 2013; 132: e1539-1545. Available in: http://dx.doi.org/10.1542/peds.2013-2149.

  21. Muthuri SG, Venkatesan S, Myles PR, Leonardi-Bee J, Lim WS, al Mamun A, et al. Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an individual participant data meta-analysis. Influenza Other Respir Viruses. 2016; 10: 192-204. Available in: http://dx.doi.org/10.1111/irv.12363.

  22. Bueno M, Calvo C, Méndez-Echevarría A, de José MI, Santos M, Carrasco J et al. Oseltamivir treatment for influenza in hospitalized children without underlying diseases. Pediatr Infect Dis. 2013; 32: 1066-1069. Available in: http://dx.doi.org/10.1097/INF.0b013e31829e4bc.

  23. Malosh RE, Martin ET, Heikkinen T, Brooks WA, Whitley RJ, Monto AS. Efficacy and safety of oseltamivir in children: systematic review and individual patient data meta-analysis of randomized controlled trials. Clin Infect Dis. 2018; 66: 1492-1500. Available in: http://dx.doi.org/10.1093/cid/cix1040.

  24. Wang K, Shun-Shin M, Gill P, Perera R, Harnden A. Neuraminidase inhibitors for preventing and treating influenza in children. Cochrane Database Syst Rev. 2012; 1: http://dx.doi.org/10.1002/14651858.CD002744.pub3. CD002744.

  25. Michiels B, van Puyenbroeck K, Verhoeven V, Vermeire E, Coenen S. The value of neuraminidase inhibitors for the prevention and treatment of seasonal influenza: A systematic review of systematic reviews. PLoS One. 2013; 8: e60348. Available in: http://dx.doi.org/ 10.1371/journal.pone.0060348, e60348.




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Rev Latin Infect Pediatr. 2019;32