2019, Number 2
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Rev Educ Bioquimica 2019; 38 (2)
El papel de las GalNac-Transferasas en el desarrollo del cáncer de mama
García CLM, Hernández JJ, Fernández RB, Hernández CPA, Pérez CME, Gallegos VIB
Language: Spanish
References: 28
Page: 48-56
PDF size: 357.72 Kb.
ABSTRACT
Breast cancer is the second cause of death of women in the world and when it is
diagnosed opportunely can be cured. Recently it has been observed that changes in
the oligosaccharides structures of membrane proteins are related to the transformation
processes and cellular proliferation, in addition, the presence of receptor for
these carbohydrates, can potentialise the metastatic capacity of the tumor. In this
revision a general overview of the glycosylated markers and their receptors, especially
galectin-3 that, has been associated to breast cancer.
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