2019, Number S1
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ABSTRACTNo abstract.The ideal ovarian stimulation regimen for IVF should have a low cancelation rate, minimize drug costs, have low risks and side effects, and maximize singleton pregnancy rates. Individualization starts from an assessment before the start of IVF cycle of the ovarian reserve by antral follicle count (AFC), antimullerian hormone (AMH), FSH, and age of the patient. Once the patient is categorized as a hypo/hyper or normoresponder the dose of gonadotropin is decided. The selection of dose is of paramount importance for optimal outcome of controlled ovarian stimulation (COS). This helps in explaining the prognosis and in appropriate counseling and also ensures a safe controlled ovarian stimulation. In women at high risk for ovarian stimulation, it is important to start with low doses and intensive monitoring. In case there are indications of hyperstimulation, the regime may be altered by decreasing dose or coasting. Many factors are interdependent, and hence, a careful selection of the type of ovarian stimulation will be the key factor in deciding the success of the same.
Drakopoulos P, Blockeel C, Stoop D, Camus M, de Vos M, Tournaye H et al. Conventional ovarian stimulation and single embryo transfer for IVF/ICSI. How many oocytes do we need to maximize cumulative live birth rates after utilization of all fresh and frozen embryos? Hum Reprod. 2016; 31 (2): 370-376.