2019, Number 3
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Rev Mex Pediatr 2019; 86 (3)
Acute encephalitis as a complication of varicella in a child
Liborio-Neto AO
Language: Spanish
References: 14
Page: 119-122
PDF size: 156.47 Kb.
ABSTRACT
Introduction: Varicella o chickenpox is a highly contagious disease. Varicella is spread worldwide and is caused by the varicella zoster virus. Despite the perception that it is a benign pediatric disease, complications are expected in about 2 to 5%. The neurological involvement may vary from aseptic meningitis to encephalitis. Viruses are the most common infectious agents associated with acute encephalitis, of which 22% occur due to chickenpox.
Objective: To report a varicella case of a seven-year-old male patient who developed acute encephalitis.
Case description: A seven-year-old patient admitted to the emergency department due to a history of vesicular-papule-crusted skin lesions on the face, trunk and limbs. Three days later, the patient evolved with prostration, altered alertness, drowsiness and vomiting. The established therapy was with intravenous acyclovir, resulting in improvement of neurological symptoms and skin lesions.
Conclusions: Every patient with chickenpox should be carefully evaluated for possible complications, including the neurologicals. Where appropriate, timely detection will help to offer specific treatment to avoid further damage.
REFERENCES
Hirose M, Gilio AE, Esposito-Ferronato A, Lopes-Betta-Ragazzi S. Impacto da vacina varicela nas taxas de internações relacionadas à varicela: revisão de dados mundiais. Revista Paulista de Pediatria. 2016; 34(3): 359-366.
Bozzola E, Bozzola M. Varicella complications and universal immunization. J Pediatr (Rio J). 2016; 92: 328-330.
Silva MT. Viral encephalitis. Arq Neuropsiquiatr. 2013; 71(9B): 703-709. doi: 10.1590/0004-282X20130155.
Becerra JC, Sieber R, Martinetti G, Costa ST, Meylan P, Bernasconi E. Infection of the central nervous system caused by varicella zoster virus reactivation: a retrospective case series study. International J Infect Dis. 2012; 17(7): e529-e534
Brito MJ, Luis C, Silva R, Gouveia C, Vieira JP. Encefalites-Recomendações da Sociedade de Infecciologia Pediátrica e da Sociedade Portuguesa de Neuropediatria. Acta Pediatr Port. 2011; 42(6): 284-291.
Ratola A, Almeida A, Quaresma L, Flores MM, Nordeste A. Internamentos por varicela em pediatria: casuística de um Hospital Nível 2. Nascer e Crescer. 2014; 23(4): 185-189.
Lizarazo J, Castellanos MF, Omaña CR, Chaín M, Villamizar S. Intracerebral hemorrhage caused by varicella-induced thrombocytopenia. Biomédica [online]. 2016; 36(suppl. 2): 10-13. ISSN 0120-4157. Disponible en: http://dx.doi.org/10.7705/biomedica.v36i0.2917.
Yucumá-Gutiérrez S, González-Manrique G, Alzate-Carvajal V, Mondragón-Cardona A. Caracterización de la mielitis transversa en un hospital referencia del sur colombiano. Acta Med Peru. 2017; 34(1): 23-26.
Delagnelo-Baby D. Complicações de varicela em crianças internadas no Hospital Infantil Joana de Gusmão. 52 F. [Trabalho de conclusão de curso]. Santa Catarina: Universidade Federal de Santa Catarina; 2007.
Anjos KS, Ferreira MM, Arruda MC, Silva-Ramos K, Regazzi-Magalhaes AP Caracterização epidemiológica dos casos de varicela em pacientes internados em um hospital universitário da cidade do Recife. Rev Bras Epidemiol. 2009; 12(4): 523-532.
Fernandes S, Rocha G, Januario L. Hospitalizações por varicela no Hospital Pediátrico de Coimbra (2000-2007). Acta Pediatr Port. 2010; 41(5): 205-208.
Villaseca KA. Varicela: indicaciones actuales de tratamiento y prevención. Rev Chil Infect. 2004; 21(Supl 1): S20-S23.
Vázquez M, Cravioto P, Galván F, Guarneros D, Pastor VH. Varicela y herpes zóster: retos para la salud pública. Salud Publica Mex. 2017; 59: 650-656. https://doi.org/10.21149/7997
Martino-Mota A, Carvalho-Costa FA. Varicella zoster virus related deaths and hospitalizations before the intro-duction of universal vaccination with the tetraviral vaccine. J Pediatr (Rio J). 2016; 92: 361-366.