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2019, Number 5

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Med Int Mex 2019; 35 (5)

Stauffer’s syndrome as manifestation of clear cell renal carcinoma

Núñez-Barreiro LR, Echave-Ávalos JA, Gutiérrez-Cota F
Full text How to cite this article

Language: Spanish
References: 7
Page: 807-812
PDF size: 738.31 Kb.


Key words:

Stauffer syndrome, Clear cell renal carcinoma, Paraneoplastic syndrome.

ABSTRACT

The incidence of clear cell renal carcinoma corresponds to about 2% of all malignant neoplasms. The classic triad of hematuria, abdominal pain and palpable mass is estimated in 10% of cases. Stauffer described in 1961 the first case called nonmetastatic hepatophrenic dysfunction syndrome, this condition can be found in 3 to 20% of cases. The involvement of liver enzymes may be related to metastatic liver infiltration or also due to non-metastatic dysfunction. It is a rare manifestation in renal cancer. Before the finding of elevated liver enzymes and alkaline phosphatase, ruling out both anatomic and functional hepatic impairment, Stauffer syndrome should be suspected, being able to make the difference between going unnoticed or being a timely finding. This paper reports a little frequent manifestation of paraneoplastic syndrome of clear cell renal carcinoma.


REFERENCES

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  2. Fernández Delgado C, Rovai BG, Rapado Errazti A, Vela Navarrete R. Síndrome de Stauffer o hiperfosfatemia como síndrome paraneoplásico del hipernefroma. REEMO 2001;10(4).

  3. Campbell SC, Novick AC, Bukowski RM. Neoplasm of the upper urinary tract. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Craig CA, editors. Campbell-Walsh Urology. 9th ed. Chapter 47 [CD-ROM]. Philadelphia: Saunders Elsevier; 2007.

  4. Tomadoni A, García C, Márquez M, Ayala J, Prado F. Síndrome de Stauffer con ictericia, una manifestación paraneoplásica del carcinoma renal: a propósito de un caso. Archivos Españoles de Urología 2010;63(2):154- 156.

  5. Hinostroza Yanahuaya J, Mon-Mon C, Ortega Marcos O, Herrero Berrón JC, Ortiz Libreros M, Vigil Medina A. Síndrome de Stauffer y carcinoma de próstata, dos casos en pacientes de hemodiálisis crónica. Nefrología 2013. doi: 10.3265.Nefrologia.pre2013.May.10953

  6. Motta-Ramírez GA, Cabrera-Aleksandrova T, Velázquez- Martínez E, Urbina-De la Vega F, Herrera-Ascencio E, Velasco M. Síndromes paraneoplásicos y cáncer renal, presentación de 2 casos. Acta Médica Grupo Ángeles 2010;8(2).

  7. Rodríguez Collar T, Pérez Pérez M, Borges Sandrino R, Romero Calderón D. Síndrome de Stauffer en paciente con adenocarcinoma renal. Revista Cubana de Urología 2017;6(2):84-92.




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C?MO CITAR (Vancouver)

Med Int Mex. 2019;35