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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2019, Number 12

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Ginecol Obstet Mex 2019; 87 (12)

Difference in neutrophil/lymphocyte index between patients with polycystic ovarian syndrome and healthy women

Carranza-Lira S, Rodríguez-Acosta GC, Hernández-Ángeles LCE
Full text How to cite this article

Language: Spanish
References: 15
Page: 802-806
PDF size: 234.76 Kb.


Key words:

Neutrophil/lymphocyte index, Glucose, Lipids, Cardiovascular diseases, Risk factors, Androstenedione.

ABSTRACT

Objective: To determine the difference in the neutrophil/lymphocyte index between PCOS patients and healthy women.
Materials and Methods: Descriptive, retrospective, cross-sectional, comparative study. Women with PCOS were studied in which glucose, lipids, testosterone, androstenedione and dehydroepiandrosterone sulfate were measured, also a blood count was performed, and the neutrophil/lymphocyte index was calculated. The results were compared with healthy controls studied for infertility. For statistical analysis, Mann- Whitney U and Spearman correlation analysis were used.
Results: 112 patients divided as follows were studied: group I with PCOS (n = 63) and group II healthy women (n = 49). The median age was for group I: 27 (14-39) and group II: 28 (16-41) years without statistically significant difference between them, also there were not between the groups in the concentrations of glucose, cholesterol and triglycerides. The neutrophil/lymphocyte index was significantly higher in the group with PCOS, 1.9 (0.9-7.4) vs 1.4 (0.8-3.9), p ‹ 0.000, respectively.
Conclusion: PCOS is associated with a chronic inflammatory process that may confer greater cardiovascular risk.


REFERENCES

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Ginecol Obstet Mex. 2019;87