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Revista Médica Sinergia

2019, Number 11

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Revista Médica Sinergia 2019; 4 (11)

Update in the Guillain-Barré Syndrome

Phillips MÓ

Language: Spanish
References: 17
Page: 290
PDF size: 141.04 Kb.


ABSTRACT

Guillain-Barre Syndrome (GBS) is one of the most frequent peripheral neuropathies in the world, which has Campylobacter jejuni infection and some immunizations as the most common triggers; Likewise, it has been possible to determine an antibody-mediated immune response, complement activation and macrophage recruitment against the axons of nerve cells or myelin sheaths of peripheral neurons. According to the clinical criteria, to diagnose GBS the presence of progressive weakness in the extremities is required, as well as arreflexia; additionally, are evaluated: the evolution of the symptoms from 2 to 4 weeks, the presence of sensitive, autonomic and cranial nerve symptoms, bilateral facial weakness, electrodiagnostic findings, albuminocytological dissociation and progressive recovery of symptoms. Treatment continues to be based on the administration of intravenous gamma globulin and plasmapheresis.


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