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2019, Number 2

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Sal Jal 2019; 6 (2)

Prevalencia de daño renal en pacientes de reciente diagnóstico con infección por VIH sin experiencia con antirretrovirales (naïve)

Corona-Ruiz F, Rodríguez-Toledo A, Rodríguez-Ruiz JA
Full text How to cite this article

Language: Spanish
References: 20
Page: 110-115
PDF size: 230.77 Kb.


Key words:

Kidney damage, Human Immunodeficiency Virus, Chronic Kidney Disease, Prevalence.

ABSTRACT

Chronic kidney disease (CKD) is a significant cause of morbidity in patients infected with the Acquired Immune Deficiency Virus (HIV). The prevalence of CKD in patients with HIV is estimated between 5-30%. There are factors that can influence the development of kidney damage such as low CD4 + lymphocytes or high blood virus values. This affects the decision of the initial treatment. Objective: Relate renal function in patients with HIV infection inexperienced antiretroviral (naïve) with levels of CD4 + lymphocytes. Materials and Methods: The present study is a prevalence study, which is a descriptive, retrospective cross-sectional design. General variables sex and age of patients. Analytical variables such as CD4 +, viral load, urea, and creatinine. Results: A 119 patients were included, 93.2% of male, the average age was 32 years, mean creatinine 0.87 mg/dL, mean Urea 24.4 mg/dL, eGFR CKD-EPI average 112 mL/ min/1.73m2, CD4 + on average 363 mm3 cells and viral load average 334.671 copies/ml. Proteinuria in 16.6% of patients. The prevalence of 14.8% of the renal damage was found. The association of kidney damage with low CD4 + counts P = 0.0001. There is also an association with high viral load. P = 0.0001. Conclusions: The prevalence of renal damage was moderate. It is important always to a scrutiny of kidney damage in patients diagnosed with HIV.


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Sal Jal. 2019;6