2006, Number 2
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Rev Mex Cardiol 2006; 17 (2)
Inflammation and insulin resistance: Mechanisms for the atherosclerosis and endothelial dysfunction development
González CA, Malanco HLM, Sánchez ZMJ, Elizondo AS, Navarro ZJE, Rosillo RS
Language: Spanish
References: 31
Page: 71-82
PDF size: 127.26 Kb.
ABSTRACT
It is observed a positive co-relation between insulin resistance and high levels of inflammatory markers (among them we find the High Sensibility Protein C Reactive), both, as medical evidence shows, are associated with an increase to develop Diabetes Mellitus Type 2 and Cardiovascular Disease. It is important to analyze the role of inflammation and insulin resistance as mechanisms that could help to develop endothelial dysfunction and atherosclerosis, as well as their relation with metabolic process (overflow and portal theories). The use of this knowledge allows us to have a general vision about the “anti-inflammatory activity of diverse drugs”.
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