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Federación Mexicana de Ginecología y Obstetricia, A.C.

2020, Number 04

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Ginecol Obstet Mex 2020; 88 (04)

Obstetric outcomes in pregnant women with chronic kidney disease and associated factors

Guzmán-Solís MC, Sánchez-Rodríguez O, Montaño-Martínez A, Peredo-Villa DE, Paniagua-Sierra R, Trejo-Villeda MÁ, Hernández-Rivera JCH

Language: Spanish
References: 24
Page: 230-243
PDF size: 245.94 Kb.


ABSTRACT

Objective: To know the factors associated with fetal, maternal and renal outcomes in known pregnant women with chronic kidney disease.
Materials and Methods: An observational, prospective study at the IMSS Hospital of Gynecobstetrics No. 4 from 2016 to 2018 of pregnant women with chronic kidney disease with biochemical parameters (creatinine, urea) and obstetric outcomes; Incomplete cases were excluded. For the type of population, non-parametric statistics were used with median (central tendency), interquartile range (dispersion), for the comparison of means, a student's “t” was used, with a significance of p ‹ 0.05 and Kruskal Wallis. To establish risk, a bivariate analysis is performed. SPSS 25 statistical program.
Results: The obstetric results obtained were: 16/48 of the women with preeclampsia, caesarean section was the most common resolution in 32/48 cases. In relation to newborns, 41 survived, 22/41 with prematurity, 19/41 were full term, 29/41 newborns without complications. There was an elevation of 0.28 mg/dL creatinine and a decrease in the glomerular filtration rate of 9.67 mL/min.
Conclusions: 4 factors were identified. Pulmonary maturation and chronicdegenerative diseases represented a risk for prematurity; Two influential factors for the termination of pregnancy were: not taking preeclampsia and having no hospitalization and/or infection events. chronic kidney disease directly influences both maternal and fetal adverse outcomes, and pregnancy also has an influence on greater renal impairment.


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