medigraphic.com
SPANISH

Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2020, Number 05

<< Back Next >>

Ginecol Obstet Mex 2020; 88 (05)

Phyllodes tumor of the breast: experience in the diagnosis, treatment and follow-up of 28 cases in Colombia

Guio-Ávila JI, Parra-Medina R, Fajardo-Cuéllar AM, Velasco-Plazas NS, Reyes-Skinner C
Full text How to cite this article

Language: Spanish
References: 20
Page: 283-292
PDF size: 258.49 Kb.


Key words:

Phyllodes tumor, Mastectomy, Breast neoplasms, Mastectomy segmental, Biopsies, Management, Quadrantectomy.

ABSTRACT

Objective: Describe the experience of diagnosis, treatment and follow-up of patients with phyllodes tumor who consulted in two institutions in Bogotá, in a period of 6 years.
Materials and Methods: A descriptive case series study was carried out, where clinical histories and reports of surgical pathology of patients with a diagnosis of PT who attended a mastology consultation at the San José Hospital and San José University Children's Hospital in January were reviewed. from 2013 to June 2019. Imaging studies, preoperative biopsies, surgical management, final pathology report and posttreatment follow-up were analyzed. A database with sociodemographic and clinical characteristics of interest was tabulated.
Results 15 of 28 benign cases, 7 of 28 malignant cases and 6 of 28 borderline cases were reported, the median age was 49.3 years (RIC 43.5 -57), Trucut biopsy identified 18/28 of phyllodes tumor. Ultrasound studies were reported as BIRADS 4 in 18/28. The surgical management was quadrantectomy and mastectomy according to the size of the lesion. No deaths were reported.
Conclusions: Phyllodes tumor is a tumor of rapid growth, low incidence, frequent in the fifth and sixth decade of life, however, cases are recorded at extreme ages (15- 74 years). Its main symptom is palpable mass and in imaging studies it manifests itself as suggestive lesions of malignancy (BIRADS 4). Surgical management is considered as the treatment pillar.


REFERENCES

  1. Ossa CA, et al. Phyllodes tumor of the breast: a clinicpathologic study of 77 cases in a Hispanic cohort. Colombia Médica 2015;46 (3): 104-8.

  2. Demian GA, et al. Phyllodes tumors of the breast: Analysis of 35 cases from a single institution. Journal of the Egyptian National Cancer Institute 2016; 28(4): 243-8. https://doi. org/10.1016/j.jnci.2016.06.004

  3. Ayadi-Kaddour A, et al. Malignant phyllodes tumor of the breast with liposarcomatous differentiation and intraductal hyperplasia. Breast Disease 2015; 35 (1): 59-62. doi: 10.3233/BD-140377

  4. Sarmiento MA, Laverde MC. Calidad de vida en Colombia: encuesta del DANE, 2014. Ploutos. 2017; 6 (1): 32-9. https://journal.universidadean.edu.co/index.php/plou/ article/view/1577

  5. Corso D, et al. Tumor filodes. Estado del arte. Revista Colombiana de Cancerología 2016; 20 (2): 79-86. doi. org/10.1016/j.rccan.2015.10.001

  6. Santos S JA, et al. Tumor filodes de la mama: características clínicas, en imagen y anatomopatológicas a propósito de 18 casos. Revista Chilena de Radiología 2007; 13: 90-7. doi. org/10.4067/S0717-93082007000200008

  7. Zhou ZR, et al. Diagnostic performance of core needle biopsy in identifying breast phyllodes tumors. Journal of Thoracic Disease 2016; 8 (11): 3139. 10.21037/jtd.2016.10.109

  8. Dillon MF, et al. Needle core biopsy in the diagnosis of phyllodes neoplasm. Surgery 2006; 140 (5): 779-84. https:// doi.org/10.1016/j.surg.2006.03.022

  9. Marcil G, et al. Fibroepithelial breast lesions diagnosed by core needle biopsy demonstrate a moderate rate of upstaging to phyllodes tumors. Amer J Surgery. 2017; 214 (2): 318-22. https://doi.org/10.1016/j.amjsurg. 2016.12.017

  10. Yasir S, et al. Significant histologic features differentiating cellular fibroadenoma from phyllodes tumor on core needle biopsy specimens. American Journal of Clinical Pathology 2014; 142 (3): 362-9. https://doi.org/10.1309/ AJCPZUZ96RESGPUP

  11. Tsang A K H, et al. Phyllodes tumours of the breast–differentiating features in core needle biopsy Histopathology, 2011; 59 (4): 600 – 608. DOI 10.1111/j.1365-2559.2011.03939.x

  12. Boubacar E, et al. Phyllodes tumors of the breast: Clinicopathological analysis of 106 cases from a single institution. Breast disease. 2018; 37. doi. 10.3233/BD-170297

  13. Gradishar WJ, et al. Breast Cancer Version 2.2015. J Natl Compr Canc Netw. 2015; 13 (4): 448-75. doi10.6004/ jnccn.2015.0060

  14. Chao X, et al. Adjuvant radiotherapy and chemotherapy for patients with breast phyllodes tumors: a systematic review and meta-analysis. BMC Cancer. 2019; 19 (1):372. https:// doi.org/10.1186/s12885-019-5585-5

  15. Adesoye T, et al. Current trends in the management of phyllodes tumors of the breast. Ann Surg Oncol. 2016; 23 (10): 3199-205. https://doi.org/10.1245/s10434-016-5314-0

  16. Mituś JW, et al. Treatment of Patients with Distant Metastases from Phyllodes Tumor of the Breast. World J Surg. 2016; 40 (2): 323-8. https://doi.org/10.1007/s00268-015-3262-7

  17. Jang JH, et al. Clinicopathologic risk factors for the local recurrence of phyllodes tumors of the breast. Annals of surgical oncology. 2012; 19 (8): 2612-7. Doi.org/10.1245/ s10434-012-2307-5. https://doi.org/10.1245/s10434- 012-2307-5

  18. Morales-Vásquez F, et al. Adjuvant chemotherapy with doxorubicin and dacarbazine has no effect in recurrencefree survival of malignant phyllodes tumors of the breast. Breast J. 2007;13(6):551-6. Doi.org/10.1111/j.1524- 4741.2007.00510.x

  19. Zhou ZR, et al. Phyllodes tumors of the breast: diagnosis, treatment and prognostic factors related to recurrence. J Thorac Dis. 2016; 8(11): 3361-8. 10.21037/jtd.2016.11.03.

  20. Spitaleri G, et al. Breast phyllodes tumor: a review of literature and a single center retrospective series analysis. Crit Rev Oncol Hematol. 2013; 88 (2): 427-36. https://doi. org/10.1016/j.critrevonc.2013.06.005




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Ginecol Obstet Mex. 2020;88