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Federación Mexicana de Ginecología y Obstetricia, A.C.

2020, Number 06

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Ginecol Obstet Mex 2020; 88 (06)

Renal length and creatinine clearance in pregnant patients with chronic kidney disease

Vázquez-Rodríguez JG, García-Bello JA

Language: Spanish
References: 13
Page: 372-379
PDF size: 388.06 Kb.


ABSTRACT

Objective: To measure renal length by ultrasound and creatinine clearance to assess its correlation in pregnant patients with chronic kidney disease (CKD).
Materials and Methods: Cross-sectional, analytical and retrospective study in pregnant patients with CKD whose right, left and total renal length was measured by ultrasound and the creatinine clearance calculated with the Modification of Diet in Renal Disease (MDRD) equation to evaluate its correlation. as a group and by gestational trimesters. Descriptive statistics, one-way ANOVA test and Pearson's correlation coefficient (r) were used with the SPSS version 20 statistical program. The p ‹ 0.05 and r › 0.1 value was considered significant, respectively.
Results: 50 patients were studied. The right renal length was 75.52 ± 16.14 mm, left 84.46 ± 16.51 mm and total 159.96 ± 28.59 mm. The mean creatinine clearance was 34.17 ± 25.63 mL/min/1.73 m2 body surface area. The correlation was positive for the left renal length vs creatinine clearance (r = 0.362) and total renal length vs creatinine clearance (r = 0.346) with more evidence in second trimester patients. The first trimes- ter patients were older (p = 0.004), smaller kidneys (p = 0.008), reduced creatinine clearance (p = 0.001) and higher frequency of terminal chronic kidney disease (18%).
Conclusions: An increase in left kidney length, total kidney length and ACr was found, whose correlation was positive. The changes were evident in second trimester pregnant patients.


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