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2001, Number 2

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Cir Gen 2001; 23 (2)

Thyroid nodule. Frequency of malignancy

Zaldívar RFR, López LJA, Hurtado-López LM
Full text How to cite this article

Language: Spanish
References: 7
Page: 92-94
PDF size: 32.69 Kb.


Key words:

Thyroid, neoplasm, thyroid nodule, thyroidectomy.

ABSTRACT

Objective: To inform the incidence of cancer in the thyroid nodule.
Setting: Third level health care hospital.
Design: Retrospective, transversal, descriptive study.
Patients and methods: We reviewed the clinical records of 1,038 patients subjected to surgery due to thyroid pathology in the General Surgery Ward of the General Hospital of Mexico City during 5 years, of which 630 manifested clinically as thyroid nodules. We analyzed the following variables: A) Independents: age, gender, radiation and thyroid cancer antecedents, size and location of the nodule, evolution time; B) Dependent: Histopathologic diagnosis.
Results: Four hundred twenty-five nodules corresponded to benign pathology (67.5%) and 205 (32.5%) to cancer, average age was 43 years, median of 42, mode of 52, and SD ± 16.4. The most frequent cancer was papillary carcinoma (86.6%), followed by follicular (6.8%), medullar (5.9%), and lymphoma (0.5%).
Conclusion: The clinical presentation of a single thyroid nodule is becoming more frequent, with increasing malignancy. Papillary cancer (86.6%) was the most frequently found through histopathology.


REFERENCES

  1. Tan GH, Gharib H. Thyroid incidentalomas: management approaches to non palpable nodules discovered incidentally on thyroid imaging. Ann Intern Med 1997; 126: 226-31.

  2. Gharib H. Simple thyroid nodule In: Bardin CW, ed. Current therapy in endocrinology and metabolism. Mosby-Yearbook USA. 1997: 112-117.

  3. Rodríguez-Cuevas S, Labastida Almendaro S, Reyes Cardoso JM, Rodríguez Maya E. Papillary thyroid cancer in México: review of 409 cases. Head Neck 1993; 15: 537-46.

  4. Gharib H. Changing concepts in the diagnosis and management of thyroid nodules. Endocrinol Metab Clin North Am 1997; 26: 777-800.

  5. Vázquez Ortega R, Basurto Kuba E. Nódulo tiroideo solitario: experiencia en 239 pacientes. Cir Gen 1998; 20: 99-101.

  6. Madrid-Franco JR, Baquera Heredia J, Herrera H, Aguirre Niebla A, Olío J, Sánchez L. Cáncer de tiroides en la principal zona bociógena de México. Cir Gen 1999; 21: 31-4.

  7. Basurto Kuba E, Garza Flores JH, Vázquez Ortega R, Mainero Alvarado F, Pulido Cejudo A, Hurtado López LM. Patología quirúrgica de la glándula tiroides. Experiencia de 20 años en el Hospital General de México. Cir Gen 1998; 20: 89-91.




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C?MO CITAR (Vancouver)

Cir Gen. 2001;23