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Revista Médica Sinergia

2020, Number 10

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Revista Médica Sinergia 2020; 5 (10)

Safinamide as a complementary treatment with levodopa for Parkinson's disease in the middle or advanced stages

Mc Donald MC, Tully SS, Lizano SM

Language: Spanish
References: 23
Page: 1-9
PDF size: 172.78 Kb.


ABSTRACT

Safinamide is a novel drug with both dopaminergic and non-dopaminergic effects. Its mechanism works as a selective reversible inhibitor of monoamine oxidase-B approved as a complementary treatment to levodopa in patients with mid-to-late Parkinson's disease and motor fluctuations. Safinamide does not cause new dyskinesia or worsen the existing one but is able to reduce this symptom in these patients.


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