2020, Number 3
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Dermatología Cosmética, Médica y Quirúrgica 2020; 18 (3)
Line Sign: Histopathological Finding in Diagnosis of Morphea at Dr. Manuel Gea González General Hospital
Amutio BF, Colmenero MJO, Vega MME
Language: Spanish
References: 9
Page: 178-181
PDF size: 329.04 Kb.
ABSTRACT
Background: localized scleroderma or morphea, is an idiopathic
inflammatory disease characterized by thickening of the
skin, more frequently in women (2.6:1). Histopathological findings
are essential for the diagnosis.
Objective: determine the presence of the “line sing” as histopathological
finding in patients with morphea.
Methods: a retrospective review of 30 biopsies of morphea,
to determine the presence of a new histological finding called
“line sing” a prominent, straight interface between subcutis and
adjacent collagen. Helpful for the diagnosis.
Results: after analyzed 30 biopsies, only in 13 (43.3%) the “line
sing” was observed.
Conclusions: the histopathological “line sign” is useful for the
diagnosis of morphea, however this is a new histological finding,
and there are only a few reported cases. More comparative
studies should be performed to confirm it.
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