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2020, Number 4

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Rev Hematol Mex 2020; 21 (4)

Clinical and hemogram characterization of patients with pneumonia due to COVID-19 in Veracruz, México

Del Carpio-Orantes L, García-Méndez S, Contreras-Sánchez ER, González-Segovia O, Ahumada-Zamudio A, Velasco-Caicero AR, Aparicio-Sánchez EE, arcía-Hernández O, Munguía-Sereno, ÁE, Escobar-Huerta A, Pacheco-Pérez EJ, Segura-Rodríguez OI

Language: Spanish
References: 8
Page: 205-209
PDF size: 238.31 Kb.


ABSTRACT

Background: COVID-19 disease is defined by the presence of cough, fever, or headache accompanied by at least one of the following: dyspnea, arthralgia, myalgia, odynophagia, rhinorrhea, conjunctivitis, or chest pain in the past seven days. In Chinese and European series leukopenia, lymphopenia and thrombocytopenia.
Objective: To characterize the clinical symptoms and hemogram of patients with pneumonia due to COVID-19.
Material and Methods: Descriptive, analytical and retrospective study done during April and May 2020 including patients older than 18 years who had a confirmed hosdiagnosis of pneumonia secondary to SARS-CoV-2 infection respect their symptoms and changes in blood count.
Results: We included 100 patients with a confirmed diagnosis of COVD-19 pneumonia, 46 (46%) women and 54 (54%) men, with a mean age of 49.4 ± 19.3 years. The main symptoms reported were: Fever (96%), cough (95%) and dyspnea (85%), followed by headache (83%) and arthralgia/myalgia (80%), other atypical symptoms stood out, such as anosmia/dysgeusia (75%), diarrhea (50%), abdominal pain (40%), dermatitis or rash (18%). Regarding the red formula, only 5 patients (5%) presented hypochromic microcytic anemia. The mean white blood cell count was 10,103 ± 4289 cell/mm3, neutrophils 8509.3 ± 4216 cell/mm3 and lymphocytes were 1112.7 ± 585.4 cell/mm3 and the mean platelet count was 258,548 ± 127,947 cell/mm3.
Conclusions: In the blood count analysis, the main element to consider is lymphopenia. In severe cases with poor prognosis, the presence of neutrophilia with normal leukocytes or leukocytosis and severe lymphopenia, as well as a tendency to platelet disease highlighted.


REFERENCES

  1. Del Carpio-Orantes L. Del 2019-nCoV al COVID-19, caracterizando la enfermedad. Med Int Méx 2020; 36 (3): 414-417. https://doi.org/10.24245/mim.v36i3.4009

  2. Del Carpio-Orantes, L. Covid-19, Breviario Clínico. Editorial: Autoreseditores, 1ª ed. México, 2020.

  3. Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez- Ocampo, et-al. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Preprints 2020, 2020020378. doi: 10.20944/preprints202002.0378. v1

  4. Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of Coronavirus Disease 2019 in China [published online ahead of print, 2020 Feb 28]. N Engl J Med 2020. doi: 10.1056/ NEJMoa2002032

  5. Sun P, Qie S, Liu Z, Ren J, Li K, Xi J. Clinical characteristics of 50466 hospitalized patients with 2019‐nCoV infection. J Med Virol 2020. doi: 10.1002/jmv.25735

  6. Informe nº 32. Situación de COVID-19 en España a 21 de mayo de 2020. Equipo COVID-19. RENAVE. CNE. CNM (ISCIII).

  7. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72,314 cases from the Chinese Center for Disease Control and Prevention [published online ahead of print, 2020 Feb 24]. JAMA 2020. doi: 10.1001/jama.2020.2648

  8. Chen J, Lu H, Melino G, et al. COVID-19 infection: the China and Italy perspectives. Cell Death Dis 2020; 11 (6): 438. doi: 10.1038/s41419-020-2603-0




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