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Revista Cubana de Investigaciones Biomédicas

ISSN 1561-3011 (Electronic)
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2020, Number 2

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Rev Cubana Invest Bioméd 2020; 39 (2)

Presentation of a case of agranulocytosis caused by propylthiouracil

Ramos RA, del Busto MA
Full text How to cite this article

Language: Spanish
References: 4
Page: 1-5
PDF size: 236.27 Kb.


Key words:

agranulocytosis, hyperthyroidism, thyroid goiter.

ABSTRACT

A female 33-year-old patient with an 8-year history of diffuse thyroid goiter presents at the emergency service with shortness of breath, a 39-40ºC fever, a sore throat and palpitation of 3 days' evolution. Physical examination revealed exophthalmos, hypopigmented mucosas, a purulent pharynx dotted with whitish spots, arthralgia and tachycardia. Complementary tests found anemia, leukopenia and pancytopenia upon consumption of propylthiouracil (50 mg) for a long period. The diagnosis is agranulocytosis resulting from an adverse reaction to propylthiouracil. After being treated the patient recovered from her severe status with the use of granulocyte colony stimulating factors.


REFERENCES

  1. Roca, Goderich Dr. R. Temas de Medicina Interna, Tomo 3. Editorial Pueblo y Educación, Ciudad de La Habana. 2016

  2. Colectivo de autores. Formulario Nacional de Medicamentos de Cuba. La Habana. Cuba. Ecimed. 2014.

  3. Colectivo de autores. Farmacología Básica. La Habana. Cuba. Ecimed. 2002.

  4. Colectivo de autores. Farmacología Clínica. Tomo II. La Habana. Cuba. Ecimed.2008.




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Rev Cubana Invest Bioméd. 2020;39